Effects of Phototherapy Associated With Sprint and Squat Training on Cardiac Autonomic Modulation

NCT03566186 | Completed DMC

• 1 other identifier: U1111-1214-0497
• Study Type: interventional
• Target: 39
• Locations: 1 country
• Sites: 1

Brief Summary

Recent studies have shown positive results in the application of phototherapy for the improvement of performance and acceleration of the healing process of the body homeostasis. Among the methods used to assess the recovery post-exercise has cardiac autonomic modulation assessed by heart rate variability (HRV), a tool widely used in sports to evaluate medium global behavior of the autonomic nervous system. Objective: analyze and compare the effect of a special protocol of phototherapy using different light sources interacting with a combined training with an autonomic modulation of heart rate in different moments (baseline; tracking daily; recovery post-exercise and after training). Method: 45 male participants will be allocated from a stratified randomization into three groups: control (n=15), placebo (n=15) and group special protocol of phototherapy (n=15). Participants will perform a combined training of sprints and squats twice a week for twelve weeks divided into two phases. The application of phototherapy and placebo was administered in phase 2, after sprints and just before the squat. The phototherapy was used combine different light sources and wavelength (red and infrared). Was analyze HRV in five moments: baseline; traking daily; week target of phase I and II; after training. The weeks target consist of training sessions with greater energy expenditure (largest intensity). The sphericity of the data was tested by Mauchly test. In case of violation of the sphericity assumption, the correction of Greenhouse-Geisser was performed. The data was analyzed using analysis of variance for repeated measures (Bonferroni post-test), which provide information on the effects of time, group and interaction. All statistical analyzes assume the significance level of 5%.

Conditions

Phototherapy; Autonomic Nervous System; Training

Keywords

Photobiomodulation; Autonomic nervous system; Heart rate variability; Recovery of function; Super-pulsed laser; Led light

Outcome Measures

Primary Outcomes (1)

• Effects of phototherapy on adaptation and change of cardiac Autonomic modulation.

  Analyzed and compare the effects of phototherapy with different light sources and wavelengths applied during training combined at heart rate variability

  Baseline (captation of hear rate variability for 20 minutes) before 6 weeks (captation of hear rate variability for 20 minutes) and before 12 weeks (captation of hear rate variability for 20 minutes)

Secondary Outcomes (2)

• Effects of phototherapy on recovery of cardiac Autonomic modulation.

  During training sessions with higher energetic spending leaving for the last two weeks, composed of higher intensity - (captation of hear rate variability for 1 hour on phase 1 and phase 2).

• Effects of phototherapy on tracking daily of cardiac autonomic modulation.

  daily, after exercise and before exercise (captation of hear rate variability for 7 minutes)

Study Arms (3)

Active phototherapy group

EXPERIMENTAL

(n=12) Phase 2 training + active phototherapy Dosage applied was 30J per site (180J per muscle) to six sites on the quadriceps The MR4 LaserShower 50 4D emitter (MultiRadiance Medical, USA). The optical power was calibrated before irradiationin each participant using a Thorlabs thermal power meter(Model S322C, Thorlabs, Newton, NJ, USA).

Other: Phototherapy

Placebo group

PLACEBO COMPARATOR

(n=14) Phase 2 training + placebo phototherapy group

Other: Placebo

non-treatment control group

OTHER

(n=13) Phase 2 training + control group

Other: Passive recovery

Interventions

Phototherapy OTHER

Photobiomodulation or photobiostimulation, this technique is the application of monochromatic light that can influence cellular activity through inhibition or stimulation of chemical and biological functions.

Active phototherapy group

Placebo OTHER

The same procedures as in the active phototherapy group was applied to the placebo group; however, the emitter was disabled. The device was emit the same sounds regardless of the programmed mode (active phototherapy).

Placebo group

Passive recovery OTHER

Participants was remain sat for passive recovery supervised by an independent therapist during the period when the other groups are received recovery strategies.

non-treatment control group

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy patient (self-report);
• Male gender;

You may not qualify if:

• History of cancer;
• Smokers or alcoholics;
• Use drugs that influenced cardiac autonomic activity;
• Cardiovascular, metabolic or endocrine diseases;
• Occurrence of musculoskeletal injury during the study.

Sponsors & Collaborators

• Paulista University: lead

Study Sites (1)

Franciele Marques Vanderlei

Presidente Prudente, São Paulo, 55, Brazil

Location

MeSH Terms

Interventions

Phototherapy

Intervention Hierarchy (Ancestors)

Therapeutics

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD - Clinical Professor

Study Record Dates

• First Submitted: May 28, 2018
• First Posted: June 25, 2018
• Study Start: September 3, 2017
• Primary Completion: October 1, 2017
• Study Completion: December 19, 2017
• Last Updated: June 25, 2018

Record last verified: 2018-06

Locations

BR (1)