Acute Caffeine Effects on Cardiac Autonomic and Cardiorespiratory Parameters Responses After Aerobic Exercise

NCT02917889 | Unknown

• 1 other identifier: 44888015.8.0000.5406
• Study Type: interventional
• Target: 35
• Locations: 1 country
• Sites: 1

Brief Summary

Check the acute influence of caffeine on the autonomic modulation and cardiorespiratory parameters after aerobic exercise. Hypothesized that caffeine can promote a slower recovery of the cardiorespiratory parameters and the SNA recovery after aerobic exercise.

Conditions

Autonomic Nervous System; Cardiorespiratory Parameters

Keywords

Caffeine; Autonomic Nervous System; Recovery; Aerobic exercise

Outcome Measures

Primary Outcomes (5)

• Caffeine effects on heart rate variability (based on frequency, time domain and Chaos)

  up to 1 year

• Blood pressure (mmHg)

  Caffeine effects blood pressure recovery following aerobic exercise

  up to 1 year

• Heart rate (beats per minute)

  Caffeine effects heart rate recovery following aerobic exercise

  up to 1 year

• Respiratory rate (per minute)

  Caffeine effects arespiratory rate recovery following aerobic exercise

  up to 1 year

• Oxygen saturation pulse (oximeter-SpO2)

  Caffeine effects SpO2 recovery following aerobic exercise

  up to 1 year

Study Arms (2)

Caffeine protocol

EXPERIMENTAL

300 mg in pills

Drug: Caffeine; Other: Cardiopulmonary test; Other: Treadmill aerobic exercise

Placebo protocol

EXPERIMENTAL

300 mg in pills

Drug: Placebo; Other: Cardiopulmonary test; Other: Treadmill aerobic exercise

Interventions

Caffeine DRUG

Volunteers will consume 300 mg of caffeine in pills fifteen minutes before treadmill aerobic exercise.

Caffeine protocol

Placebo DRUG

Volunteers will consume 300 mg of placebo in pills fifteen minutes before treadmill aerobic exercise.

Placebo protocol

Cardiopulmonary test OTHER

assessment of the maximum oxygen consumption (VO2max) on a treadmill (Inbrasport / Millennium), using Buce protocol. .

Caffeine protocol; Placebo protocol

Treadmill aerobic exercise OTHER

30 mim of aerobic exercise (5 minutes at speed of 5.0 km/h for warming-up followed by 25 minutes at 60% of VO2max ).

Caffeine protocol; Placebo protocol

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• healthy men.

You may not qualify if:

• cardiovascular, orthopedic, respiratory and neurological disorders reported or other pathological conditions that prevent the subject to perform the protocols;
• smokers, alcoholics, or who use drugs that influence the activity of the heart.

Sponsors & Collaborators

• Universidade Estadual Paulista Júlio de Mesquita Filho: lead

Study Sites (1)

Universidade Estadual Paulista

Presidente Prudente, São Paulo, 19060-900, Brazil

Location

MeSH Terms

Interventions

Caffeine; Exercise Test

Intervention Hierarchy (Ancestors)

Xanthines; Alkaloids; Heterocyclic Compounds; Purinones; Purines; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, Fused-Ring; Heart Function Tests; Diagnostic Techniques, Cardiovascular; Diagnostic Techniques and Procedures; Diagnosis; Respiratory Function Tests; Diagnostic Techniques, Respiratory System; Ergometry; Investigative Techniques

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: September 19, 2016
• First Posted: September 28, 2016
• Study Start: February 1, 2015
• Primary Completion: August 1, 2016
• Last Updated: September 30, 2016

Record last verified: 2016-09

Locations

BR (1)