NCT03539107

Brief Summary

This study will compare voiding assessment based on a minimum spontaneous voided volume of 150 cc with the standard retrograde fill approach in women after pelvic floor procedures.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
110

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 15, 2018

Completed
14 days until next milestone

First Posted

Study publicly available on registry

May 29, 2018

Completed
1.3 years until next milestone

Study Start

First participant enrolled

September 1, 2019

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 20, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 20, 2019

Completed
Last Updated

January 13, 2020

Status Verified

January 1, 2020

Enrollment Period

4 months

First QC Date

May 15, 2018

Last Update Submit

January 8, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Failure rate

    The percentage of subjects who did not meet the required voiding assessment criteria and needed catheterization .

    Up to 2 days post op

Secondary Outcomes (12)

  • False pass rate

    up to 30 days after discharge.

  • Force of stream (FOS)

    Up to 2 days post op.

  • Force of stream (FOS)

    Up to 2 days post-surgery.

  • Patient Satisfaction Questionnaire for Voiding Assessment-method used

    Up to 2 days post-surgery.

  • Patient Satisfaction Questionnaire for Voiding Assessment-negative emotions

    Up to 2 days post-surgery.

  • +7 more secondary outcomes

Study Arms (2)

Spontaneous void

EXPERIMENTAL

Subjects will not have retrograde fill of bladder, rather will be required to void 150 mL spontaneously prior to discharge.

Other: spontaneous void

Retrograde bladder fill

ACTIVE COMPARATOR

Subjects will have their bladder retrograde filled with 300mL of fluid prior to a voiding trial.

Procedure: Retrograde bladder fill

Interventions

Subjects will have their bladder retrograde filled with 300mL of fluid prior to a voiding trial.

Retrograde bladder fill

Subjects will not have retrograde fill of bladder, rather will be required to void 150 mL spontaneously prior to discharge.

Spontaneous void

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All 18-year-old or older women who undergo surgery for urinary incontinence and/or pelvic organ prolapse (POP)

You may not qualify if:

  • Patients who require prolonged Foley catheter or suprapubic catheter

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yale University

New Haven, Connecticut, 06510, United States

Location

Related Publications (1)

  • Ellahi A, Stewart F, Kidd EA, Griffiths R, Fernandez R, Omar MI. Strategies for the removal of short-term indwelling urethral catheters in adults. Cochrane Database Syst Rev. 2021 Jun 29;6(6):CD004011. doi: 10.1002/14651858.CD004011.pub4.

MeSH Terms

Conditions

Urinary IncontinencePelvic Organ Prolapse

Condition Hierarchy (Ancestors)

Urination DisordersUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesLower Urinary Tract SymptomsUrological ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsProlapsePathological Conditions, Anatomical

Study Officials

  • Harmanli Oz, MD

    Yale University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 15, 2018

First Posted

May 29, 2018

Study Start

September 1, 2019

Primary Completion

December 20, 2019

Study Completion

December 20, 2019

Last Updated

January 13, 2020

Record last verified: 2020-01

Locations