NCT03513653|Unknown
Strain for Risk Assessment and Therapeutic Strategies in Patients With Acute Heart Failure (STRATS-AHF) Registry
STRATS-AHF
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STRATS-AHF
Sponsor study identifier
observational
4,312
1 country
3
Study Start
January 1, 2009
Actual (reported)Primary Completion
September 5, 2017
Actual (reported)Study Completion
December 31, 2023
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
STRATS-AHF (STrain for Risk Assessment and Therapeutic Strategies in patients with Acute Heart Failure) registry enrolled 4,312 patients hospitalized for acute HF from 3 tertiary university hospitals (Seoul National University Bundang Hospital, Seoul National University Hospital, and Chungnam National University Hospital) from January 2009 through December 2016.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 31, 2023
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 1, 2009
Actual (reported)September 5, 2017
Actual (reported)April 19, 2018
Actual (reported)May 1, 2018
Actual (reported)December 31, 2023
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
All-cause mortality
Death from any cause
up to 5 years
Hospitalization for heart failure
up to 5 years
Composite of all-cause mortality and hospitalization for heart failure
up to 5 years
Ischemic stroke
up to 5 years
Patients hospitalized for acute heart failure and underwent echocardiography with speckle-tracking imaging
1. Measurement of left ventricular ejection fraction and global longitudinal strain 2. Measurement of left atrial reservoir strain (peak atrial longitudinal strain) 3. Measurement of right ventricular global longitudinal strain
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Patients hospitalized for acute heart failure
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, 13620, South Korea
Chungnam National University Hospital
Daejeon, 35015, South Korea
Seoul National University Hospital
Seoul, 03080, South Korea
Park JJ, Park JB, Park JH, Cho GY. Global Longitudinal Strain to Predict Mortality in Patients With Acute Heart Failure. J Am Coll Cardiol. 2018 May 8;71(18):1947-1957. doi: 10.1016/j.jacc.2018.02.064.
Park JH, Park JJ, Park JB, Cho GY. Prognostic Value of Biventricular Strain in Risk Stratifying in Patients With Acute Heart Failure. J Am Heart Assoc. 2018 Oct 2;7(19):e009331. doi: 10.1161/JAHA.118.009331.
Goo-Yeong Cho, MD, PhD
Seoul National University Bundang Hospital
4,312 participants (actual enrollment reported by the registry).
First Submitted
April 19, 2018
First Posted
May 1, 2018
Study Start
January 1, 2009
Actual (reported)Coping Skills and Heart Failure: Outcomes and Mechanisms
Contact the study team to confirm eligibility.
Hwang IC, Cho GY, Choi HM, Yoon YE, Park JJ, Park JB, Park JH, Lee SP, Kim HK, Kim YJ, Sohn DW. Derivation and validation of a mortality risk prediction model using global longitudinal strain in patients with acute heart failure. Eur Heart J Cardiovasc Imaging. 2020 Dec 1;21(12):1412-1420. doi: 10.1093/ehjci/jez300.
Park JJ, Choi HM, Hwang IC, Park JB, Park JH, Cho GY. Myocardial Strain for Identification of beta-Blocker Responders in Heart Failure with Preserved Ejection Fraction. J Am Soc Echocardiogr. 2019 Nov;32(11):1462-1469.e8. doi: 10.1016/j.echo.2019.06.017. Epub 2019 Sep 17.
Park JH, Hwang IC, Park JJ, Park JB, Cho GY. Prognostic power of left atrial strain in patients with acute heart failure. Eur Heart J Cardiovasc Imaging. 2021 Jan 22;22(2):210-219. doi: 10.1093/ehjci/jeaa013.
Park CS, Park JB, Park JJ, Park JH, Cho GY. Impact of sex and myocardial function on association of obesity with mortality in Asian patients with acute heart failure: a retrospective analysis from the STRATS-AHF registry. BMJ Open. 2020 Feb 10;10(2):e031608. doi: 10.1136/bmjopen-2019-031608.
Park JJ, Mebazaa A, Hwang IC, Park JB, Park JH, Cho GY. Phenotyping Heart Failure According to the Longitudinal Ejection Fraction Change: Myocardial Strain, Predictors, and Outcomes. J Am Heart Assoc. 2020 Jun 16;9(12):e015009. doi: 10.1161/JAHA.119.015009. Epub 2020 Jun 10.
Park JJ, Park JH, Hwang IC, Park JB, Cho GY, Marwick TH. Left Atrial Strain as a Predictor of New-Onset Atrial Fibrillation in Patients With Heart Failure. JACC Cardiovasc Imaging. 2020 Oct;13(10):2071-2081. doi: 10.1016/j.jcmg.2020.04.031. Epub 2020 Jul 15.
Park JH, Kim M, Park JJ, Park JB, Cho GY. Prognostic Role of RVGLS/PASP Ratio, a New Echocardiographic Parameter of the Right Ventricle-Pulmonary Artery Coupling, in Patients With Acute Heart Failure. Int J Heart Fail. 2024 Oct 28;6(4):165-173. doi: 10.36628/ijhf.2024.0048. eCollection 2024 Oct.
Park CS, Park JJ, Hwang IC, Park JB, Park JH, Cho GY. Myocardial strain to identify benefit from beta-blockers in patients with heart failure with reduced ejection fraction. ESC Heart Fail. 2022 Apr;9(2):1248-1257. doi: 10.1002/ehf2.13800. Epub 2022 Jan 9.
Park CS, Hwang IC, Park JJ, Park JH, Park JB, Cho GY. Determinants of the survival benefit associated with statins in patients with acute heart failure. ESC Heart Fail. 2021 Dec;8(6):5424-5435. doi: 10.1002/ehf2.13637. Epub 2021 Oct 5.
Primary Completion
September 5, 2017
Actual (reported)Study Completion
December 31, 2023
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
April 12, 2023
Record last verified: 2023-04
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Source: ClinicalTrials.gov.
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