NCT00758121

Brief Summary

The objective of the study is to determine if there is any relationship between respiratory rate and Heart Failure events.

Trial Health

60
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
56

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Nov 2008

Shorter than P25 for all trials

Geographic Reach
2 countries

2 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 19, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 23, 2008

Completed
1 month until next milestone

Study Start

First participant enrolled

November 1, 2008

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2009

Completed
Last Updated

November 6, 2009

Status Verified

November 1, 2009

Enrollment Period

11 months

First QC Date

September 19, 2008

Last Update Submit

November 4, 2009

Conditions

Study Arms (1)

Observation

Heart failure patients with an implanted CRT-D

Device: Cardiac Resynchronization Therapy Defibrillator

Interventions

CRT-D observational study

Observation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Heart failure patients with an implanted CRT-D.

You may qualify if:

  • Implanted COGNIS device or future commercially available Boston Scientific CRT-D, that contains the Sensor Trend for Respiratory Rate, with a right ventricular lead and left ventricular lead actively implanted
  • Respiratory Sensor programmed "On"
  • Classified as having NYHA Class III heart failure documented, in the past 12 months
  • Age 18 or above, or of legal age to give informed consent specific to state and national law
  • Willing and capable of providing informed consent, participating in all testing associated with this clinical investigation at an approved clinical investigational center and at the intervals defined by this protocol

You may not qualify if:

  • Inability or refusal to sign the patient Informed Consent
  • Inability or refusal to comply with the follow-up schedule
  • Patients that have received routinely scheduled intravenous inotropic therapy as part of their drug regimen within the past 90 days
  • Patients prescribed to positive airway pressure therapy
  • A life expectancy of less than 180 days, per physician discretion
  • Enrolled in any concurrent study without prior written approval from Boston Scientific CRM
  • Women who are pregnant or plan to become pregnant in the next twelve months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

San Diego Cardiac Center

San Diego, California, 91213, United States

Location

UZ Brussel

Brussels, Belgium

Location

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Brian Jaski, MD

    San Diego Cardiac Center

    PRINCIPAL INVESTIGATOR
  • Pedro Brugada, MD

    Universitair Ziekenhuis Brussel

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

September 19, 2008

First Posted

September 23, 2008

Study Start

November 1, 2008

Primary Completion

October 1, 2009

Study Completion

October 1, 2009

Last Updated

November 6, 2009

Record last verified: 2009-11

Locations