Ultrasound Guided Quadratus Lumborum Block for Post Operative Analgesia After Hip Arthroplasty

NCT03502369 | Unknown DMC

• 1 other identifier: 050108004
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The study evaluates the effectiveness of anterior quadratus lumborum block for post operative analgesia after hip arthroplasty. Half of the participants will receive ultrasound guided anterior quadratus lumborum block using 30ml bupivacaine 0.375%, while the other half will not receive the block ( control group).

Conditions

Pain, Postoperative

Outcome Measures

Primary Outcomes (1)

• Pain intensity assessment

  Patients will be trained to use visual analogue scale which consists of 10cm line, 0 cm equivalent to no pain and 10 cm denoting the worst imaginable pain.

  every hour for the first 4 post operative hours and then every 4 hours for the rest of the 24 post operative hours.

Secondary Outcomes (1)

• Total amount of post operative morphine (mg).

  any time in the first 24 post operative hours.

Other Outcomes (1)

• Patient satisfaction.

  every hour in the first 4 post operative hours and then every 4 hours for the rest of the 24 post operative hours.

Study Arms (2)

QL group

EXPERIMENTAL

Anterior Quadratus lumborum block will be done for all patients of these group. Local anaesthetic (30ml of bupivacaine) will be injected in fascial plane between the quadratus lumborum muscle and Psoas major muscle by using the ultrasound.

Procedure: Anterior Quadratus lamborum block

C group

NO INTERVENTION

Patients of these group will be the control group. The will receive acetaminophen 1g every 8h, ketorolac 30mg ever 12h and as required morphine 2mg for post operative analgesia after hip arthroplasty.

Interventions

Anterior Quadratus lamborum block PROCEDURE

Local anaesthetic will be injected in the fascial plane between psoas major muscle and quadratus lumborum muscle.

Also known as: Transmuscular QL block, QL3

QL group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• American society of anesthesiologists physical status \|-\|\|\| , scheduled to undergo unilateral hip replacement via lateral approach.

You may not qualify if:

• patient refusal.
• History of neurological/neuromuscular, psychiatric, dementia preventing proper comprehension.
• coagulation disorders.
• History of allergy to the study medication.
• Infection overlying the injection site.

Sponsors & Collaborators

• Alexandria University: lead

Study Sites (1)

Alexandria faculty of medicine

Alexandria, 21519, Egypt

RECRUITING

Related Publications (2)

• Ueshima H, Otake H, Lin JA. Ultrasound-Guided Quadratus Lumborum Block: An Updated Review of Anatomy and Techniques. Biomed Res Int. 2017;2017:2752876. doi: 10.1155/2017/2752876. Epub 2017 Jan 3.

  PMID: 28154824 BACKGROUND

• Sauter AR, Ullensvang K, Niemi G, Lorentzen HT, Bendtsen TF, Borglum J, Pripp AH, Romundstad L. The Shamrock lumbar plexus block: A dose-finding study. Eur J Anaesthesiol. 2015 Nov;32(11):764-70. doi: 10.1097/EJA.0000000000000265.

  PMID: 26426575 RESULT

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Registeral

Model Details: Adult 90 orthopaedic patient ASA physical status \|-\|\|\| will be randomly allocated in two groups each one 45 patients, one group will receive the anterior quadratus lumborum block and the other group will not receive the block.

Study Record Dates

• First Submitted: April 11, 2018
• First Posted: April 18, 2018
• Study Start: September 1, 2018
• Primary Completion: January 1, 2019
• Study Completion: March 1, 2019
• Last Updated: April 19, 2018

Record last verified: 2018-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
• Time Frame: Data will be available within 6 months of study completion.

Locations

EG (1)