Short and Fast Step Test: Feasibility, Validity and Tolerance of a Functional Evaluation Test of Lactic Anaerobic Capacities in Patients With Coronary Artery Disease

NCT03491423 | Completed

• 1 other identifier: HANNEQUIN APPARA 2016
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

Recommendations for cardiovascular rehabilitation (CVR) encourage exercise training, primarily involving the aerobic system, to allow patients to regain independence in daily activities. However, the lactic anaerobic process is also involved during these activities (stair climbing, carrying loads, etc.). Hence there is a major interest in accurately assessing patients' anaerobic capacities in order to tailor suitable exercise programs. However, there are no functional tests specifically dedicated to the evaluation of lactic anaerobic metabolism and adapted to people with coronary disease. The investigators offer a dedicated test, the short and fast test (SFST), which can be applied in current clinical practice and has already been evaluated in a population of healthy subjects. The purpose of this project is to evaluate the safety, feasibility and validity of SFST in a population of patients with coronary artery disease.

Conditions

Coronary Artery Disease Without Heart Failure

Outcome Measures

Primary Outcomes (1)

• percentage of patients who completed the SFST without complications

  \- Absence of muscular or bone-joint disorders quantified according to the VAS. The exercise will be considered as not tolerated if pain is reported during the test and/or at day 3 (VAS≥6). AND no falls or stumbling related trauma AND absence of cardiovascular or blood pressure events: * Hypertension (systolic pressure greater than 250 mmHg (O'Brien et al. 2005) or hypotension with clinical consequences (malaise or feeling unwell) * Discomfort, chest pain, onset of vascular claudication * Rhythm or conduction disorders or repolarization abnormalities, at a higher frequency than that observed in the pre-inclusion stress test * Abnormal increase in heart rate (greater than the maximum rate determined during the stress test).

  through study completion, an average of 11 days

Study Arms (1)

Patients

EXPERIMENTAL

Other: Short and fast step test without measurement of pulmonary gas exchange; Biological: glucose meter; Other: ECG / heart rate; Other: questionnaires; Other: Short and fast step test with measurement of pulmonary gas exchange

Interventions

Short and fast step test without measurement of pulmonary gas exchange OTHER

For one minute, the patient should climb up and down a 17.5 cm high step as quickly as possible while holding onto a bar in front of the step.

Patients

glucose meter BIOLOGICAL

glucose meter to measure lactatemia

Patients

ECG / heart rate OTHER

ECG and heart rate (HR) collection by telemetry

Patients

questionnaires OTHER

VAS pain assessment and evaluation of effort perception according to Borg's scale

Patients

Short and fast step test with measurement of pulmonary gas exchange OTHER

For one minute, the patient should climb up and down a 17.5 cm high step as quickly as possible while holding onto a bar in front of the step.

Patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• \- Patient who has given oral consent Adult patient (male or female) with coronary artery disease without heart failure referred for rehabilitation program Left ventricular ejection fraction (Simpson method) \> 45%.

You may not qualify if:

• Protected adult
• Patient not affiliated to a national health insurance scheme
• Pregnant or breastfeeding woman
• Orthostatic hypotension
• Severe obstructive heart disease
• aortic valve narrowing
• Progressive severe cardiac rhythm or conduction disorders not requiring a device, detected during the initial stress test.
• intracavitary cardiac thrombus
• severe pulmonary arterial hypertension (systolic pulmonary hypertension \>70mmHg)
• recent venous thromboembolic history (last 3 months)
• heart transplantation
• associated medical condition that can predominantly impair functional and respiratory capacities (examples: unstabilized metabolic disorders such as progressive renal failure, significant asthenia related to a severe unstabilized condition such as neoplasia, systemic disease, chronic obstructive pulmonary disease...)
• physical impairments of the lower limbs hindering the test, whether neurological (central or peripheral), arterial (in particular, arteriopathy of the lower limbs with systolic index \< 0.6) or orthopedic (degenerative or inflammatory rheumatism)
• Treatment with Corticosteroids, Anabolics, or L-Carnitine.

Sponsors & Collaborators

• Centre Hospitalier Universitaire Dijon: lead

Study Sites (1)

CHU de DIJON

Dijon, 21079, France

Location

Related Publications (1)

• Besson D, Gouteron A, Sinssaine-Ayillo A, Casillas JM, Rigaud L, Ornetti P, Fournel I, Ksiazek E, Laroche D, Gueugnon M. Is the Short and Fast Step Test a safe and feasible tool for exploring anaerobic capacities of individuals with coronary heart disease in clinical practice? Eur J Phys Rehabil Med. 2021 Dec;57(6):977-984. doi: 10.23736/S1973-9087.21.06713-7. Epub 2021 Feb 23.

  PMID: 33619946 RESULT

MeSH Terms

Interventions

epicatechin gallate; Heart Rate; Surveys and Questionnaires

Intervention Hierarchy (Ancestors)

Vital Signs; Physical Examination; Diagnostic Techniques and Procedures; Diagnosis; Hemodynamics; Cardiovascular Physiological Phenomena; Circulatory and Respiratory Physiological Phenomena; Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 30, 2018
• First Posted: April 9, 2018
• Study Start: June 4, 2018
• Primary Completion: May 3, 2019
• Study Completion: May 3, 2019
• Last Updated: February 4, 2026

Record last verified: 2026-02

Locations

FR (1)