Neural Mechanisms of Decision Making in Hoarding Disorder

NCT03487224 | Active Not Recruiting

• 1 other identifier: 42327
• Study Type: observational
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to understand the neural mechanisms of decision making in hoarding disorder.

Conditions

Hoarding Disorder

Keywords

Hoarding Disorder

Outcome Measures

Primary Outcomes (1)

• BOLD signal

  BOLD signal derived from fMRI

  up to 90 minutes

Study Arms (2)

Hoarding Disorder

Adults diagnosed with Hoarding Disorder

Device: MRI with fMRI frequency

Healthy Controls

Adults without mental illness

Device: MRI with fMRI frequency

Interventions

MRI with fMRI frequency DEVICE

Functional magnetic resonance imaging or fMRI measures brain activity by detecting changes in blood flow. Participants will do cognitive tasks during fMRI.

Healthy Controls; Hoarding Disorder

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Individuals with Hoarding Disorder and Healthy Participants

You may qualify if:

• ages 18-70
• primary diagnosis of hoarding disorder
• sufficient severity of hoarding symptoms
• stable on psychotropic medications for 1 month prior to study enrollment
• capacity to provide informed consent
• ability to tolerate clinical study procedures
• ages 18-70
• capacity to provide informed consent

You may not qualify if:

• psychiatric or medical conditions that make participation unsafe
• pregnant or nursing females
• concurrent use of any medications that might increase the risk of participation (e.g. drug interactions)
• presence of metallic device or dental braces
• any current or lifetime psychiatric diagnosis
• current or past use of psychotropic medication
• pregnant or nursing females
• major medical or neurological problem
• presence of metallic device or dental braces

Sponsors & Collaborators

• Stanford University: lead

Study Sites (1)

Stanford University

Stanford, California, 94305, United States

Location

Related Links

• Stanford Medicine Faculty Page
• Rodriguez Lab Website

MeSH Terms

Conditions

Hoarding Disorder

Condition Hierarchy (Ancestors)

Obsessive-Compulsive Disorder; Anxiety Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: March 27, 2018
• First Posted: April 3, 2018
• Study Start: July 8, 2018
• Primary Completion (Estimated): May 30, 2026
• Study Completion (Estimated): May 30, 2026
• Last Updated: July 16, 2025

Record last verified: 2025-07

Locations

US (1)