Comparison of Treatment for Hoarding Disorder

NCT02040805 | Completed Results DMC

• 1 other identifier: CE-1304-6000
• Study Type: interventional
• Target: 323
• Locations: 1 country
• Sites: 2

Brief Summary

This study proposes to compare two forms of treatment for Hoarding Disorder (HD), a common and impairing neuropsychiatric syndrome that has a profound impact on the lives and functioning of individuals, families, and society. Specifically, we will compare a novel community-based group treatment led by individuals from the community who are not mental health professionals to the current standard of care treatment for Hoarding Disorder, Cognitive Behavioral Therapy, conducted by psychologists in a group setting. We hypothesized that both treatment types will be similarly effective in reducing hoarding severity.

Conditions

Hoarding Disorder

Keywords

compulsive hoarding; clutter; hoarding disorder

Outcome Measures

Primary Outcomes (1)

• Saving Inventory-Revised (SI-R)

  This is a 23-item self-report questionnaire that measures hoarding symptoms and their impact, including problems with acquisition, clutter, and difficulty discarding, as well as distress and impairment/interference. The SI-R is scored on a scale of 0-92. Higher scores indicate more severe hoarding, and scores of 42 and over are considered clinically significant hoarding. Although subscale scores can be calculated, this study uses total scores as the primary outcome.

  Administered at screening before start of treatment groups and after last treatment group (20 weeks later).

Secondary Outcomes (1)

• Activities of Daily Living Scale, Hoarding (ADL-H)

  Administered at baseline and after last treatment group (20 weeks later).

Study Arms (2)

Group Cognitive-Behavioral Therapy

EXPERIMENTAL

Sixteen sessions of group therapy facilitated by a psychologist.

Behavioral: Group Cognitive Behavioral Therapy

Peer Facilitated Support Group

EXPERIMENTAL

Fifteen sessions of peer-facilitated group support.

Behavioral: Peer Facilitated Support Group

Interventions

Group Cognitive Behavioral Therapy BEHAVIORAL

Group therapy over approximately 20 weeks, based on a structured manual adapted from the individual CBT workbook for hoarding by Steketee and Frost (2006). Each session will be 2 hours in length and consists of weekly check-ins, psychoeducation about hoarding, developing understanding and awareness of one's hoarding symptoms and patterns, behavior modification, cognitive restructuring, goal-setting, motivational enhancement, in vivo and imaginal exposure for discarding and acquisition, executive skills training (organization, sorting, planning, decision-making, problem-solving, etc.), guidelines on establishing "clutter buddies", and relapse prevention. Groups will be led by clinical postdoctoral psychology fellows in the Department of Psychiatry at UCSF.

Group Cognitive-Behavioral Therapy

Peer Facilitated Support Group BEHAVIORAL

Fifteen sessions of peer facilitated, group support, over the course of 20 weeks, based on a structured manualized approach (Buried in Treasures: Help for Compulsive Acquiring, Saving, and Hoarding). Each session will be 2 hours in length. In this model, two trained peers, usually, but not necessarily, with personal lived experience of hoarding, will guide the group chapter by chapter through the Buried in Treasures manual.

Peer Facilitated Support Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of Hoarding Disorder

You may not qualify if:

• Individuals with active psychosis, schizophrenia, intellectual disability, or known dementia will be excluded
• Individuals who have participated in either cognitive-behavioral therapy for hoarding (group or individual) or in group Buried in Treasures in the past year

Sponsors & Collaborators

• University of California, San Francisco: lead
• Patient-Centered Outcomes Research Institute: collaborator

Study Sites (2)

Mental Health Association

San Francisco, California, 94102, United States

Location

University of California, San Francisco

San Francisco, California, 94143, United States

Location

MeSH Terms

Conditions

Hoarding Disorder; Speech Disorders

Condition Hierarchy (Ancestors)

Obsessive-Compulsive Disorder; Anxiety Disorders; Mental Disorders; Language Disorders; Communication Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Limitations and Caveats

The primary limitation in this study was loss to follow up. Additionally, the longitudinal follow-up assessment was post-hoc rather than being planned prior to study initiation.

Results Point of Contact

• Title: Dr. Kevin L. Delucchi
• Organization: University of California, San Francisco

kevin.delucchi@ucsf.edu

415-476-4180

Study Officials

• Carol A. Mathews, MD

  University of Florida

  PRINCIPAL INVESTIGATOR

• Kevin L. Delucchi, PhD

  University of California, San Francisco

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Two-arm parallel clinical trial with assessments pre- and post-treatment.

Study Record Dates

• First Submitted: January 16, 2014
• First Posted: January 20, 2014
• Study Start: February 1, 2014
• Primary Completion: December 31, 2016
• Study Completion: December 31, 2016
• Last Updated: February 11, 2020
• Results First Posted: February 11, 2020

Record last verified: 2020-02

Locations

US (2)