NCT03734705

Brief Summary

The present study will test a potential new treatment strategy, imaginal exposure, for hoarding disorder. Although cognitive behavioral therapy often reduces hoarding, some people do not want to start, or cannot handle, that option. To help such individuals, the present study will provide imaginal exposure therapy to people with hoarding disorder, wherein they imagine discarding possessions as a way of becoming acclimated to the idea. We predict that imaginal exposure will improve hoarding symptoms as well as two psychological experiences linked to the condition: intolerance of uncertainty and emotional avoidance.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2020

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 5, 2018

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 8, 2018

Completed
1.2 years until next milestone

Study Start

First participant enrolled

January 13, 2020

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 27, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 27, 2021

Completed
4.3 years until next milestone

Results Posted

Study results publicly available

May 29, 2025

Completed
Last Updated

May 29, 2025

Status Verified

May 1, 2025

Enrollment Period

1 year

First QC Date

November 5, 2018

Results QC Date

April 14, 2025

Last Update Submit

May 27, 2025

Conditions

Keywords

hoarding disorderintolerance of uncertaintyexperiential avoidanceimaginal exposureclutterattachment

Outcome Measures

Primary Outcomes (1)

  • Savings Inventory Revised (Frost, Steketee & Grisham, 2004; Tolin, Meunier, Frost & Steketee, 2011)

    Gold-standard 23-item self-report measure of hoarding disorder symptoms. Scale scores range from 0 to 92, with higher scores indicating more severe hoarding symptoms. More severe hoarding symptoms are considered a worse outcome.

    Baseline (Pre Writing) and Follow Up (week 1)

Secondary Outcomes (3)

  • Compulsive Acquisitions Scale (Frost et al. 2002)

    Baseline (Pre Writing) and Follow Up (week 1)

  • Intolerance of Uncertainty Scale (Buhr & Dugas, 2002)

    Baseline (Pre Writing) and Follow Up (week 1)

  • Acceptance and Action Questionnaire - II (Hayes, Luoma, Bond, Masuda and Lillis, 2006)

    Baseline (Pre Writing) and Follow Up (week 1)

Study Arms (2)

Imaginal Exposure Writing

EXPERIMENTAL

People with hoarding disorder will write for 20 minutes on each of 3 consecutive days about their worst-case scenario regarding discarding a possession (i.e., imaginal exposure).

Behavioral: Imaginal Exposure Writing

Neutral Writing

SHAM COMPARATOR

People with hoarding disorder will write for 20 minutes on each of 3 consecutive days about what they would do if they had a day off work or school.

Other: Neutral Writing

Interventions

Imaginal exposure is a psychotherapy strategy that has been studied and shown to be helpful in the improvement of symptoms (e.g., anxiety, worry) for other psychiatric conditions, including excessive worry and obsessive-compulsive disorder symptoms.

Imaginal Exposure Writing

Used in prior research as a control condition for imaginal exposure. Neutral writing will involve writing about what one would do on a day off work or school.

Neutral Writing

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 and older
  • Any gender and all ethno-racial categories
  • Hoarding Disorder primary condition
  • Willing and able to understand and complete consent and study procedures
  • English speaking

You may not qualify if:

  • Severe depression
  • Clinically at risk of suicide with Columbia Suicide Severity Rating Scale (C-SSRS) Suicidal Ideation Subscale of 4 or higher (i.e. suicidal intent without specific plan)
  • Currently receiving Cognitive Behavioral Therapy (CBT)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stanford University

Palo Alto, California, 94304, United States

Location

Related Publications (1)

  • Fracalanza K, Raila H, Avanesyan T, Rodriguez CI. Written Imaginal Exposure for Hoarding Disorder: A Preliminary Pilot Study. J Nerv Ment Dis. 2024 May 1;212(5):289-294. doi: 10.1097/NMD.0000000000001719.

    PMID: 38598729BACKGROUND

MeSH Terms

Conditions

Hoarding DisorderSpeech Disorders

Condition Hierarchy (Ancestors)

Obsessive-Compulsive DisorderAnxiety DisordersMental DisordersLanguage DisordersCommunication DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
Katie Fracalanza, PhD
Organization
Stanford University

Study Officials

  • Katie Fracalanza, PhD

    Stanford University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Participants will be randomly assigned to imaginal exposure writing intervention or neutral control writing.
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Psychiatry and Behavioral Sciences

Study Record Dates

First Submitted

November 5, 2018

First Posted

November 8, 2018

Study Start

January 13, 2020

Primary Completion

January 27, 2021

Study Completion

January 27, 2021

Last Updated

May 29, 2025

Results First Posted

May 29, 2025

Record last verified: 2025-05

Locations