Dual Site-Dual Channel Non-invasive Brain Stimulation for Language and Cognitive Function in Healthy Subjects
Effect of Dual Site-Dual Channel Non-invasive Brain Stimulation for Recovery of Language and Cognitive Function in Healthy Subjects
1 other identifier
interventional
27
1 country
1
Brief Summary
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of language and cognitive function in healthy. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on left inferior frontal cortex, ii) anodal stimulation on left dorsolateral prefrontal cortex. 2) IFG stimulation: anodal stimulation on left inferior frontal cortex; 3) DLPFC stimulation: anodal stimulation on left dorsolateral prefrontal cortex area. 4) sham stimulation
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable healthy
Started Feb 2018
Shorter than P25 for not_applicable healthy
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 28, 2018
CompletedFirst Submitted
Initial submission to the registry
March 22, 2018
CompletedFirst Posted
Study publicly available on registry
April 3, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 22, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
May 22, 2018
CompletedSeptember 20, 2019
March 1, 2018
3 months
March 22, 2018
September 19, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Korean Boston naming test
measures naming ability thorough picture naming test
Baseline and after intervention (approximately 30 minutes)
Verbal 3 back test
measure working memory
Baseline and after intervention (approximately 30 minutes)
Secondary Outcomes (2)
Korean Color Word Stroop test
Baseline and after intervention (approximately 30 minutes)
Controlled Oral Word Association Test
Baseline and after intervention (approximately 30 minutes)
Study Arms (4)
Dual stimulation
EXPERIMENTALi) anodal stimulation of left inferior frontal cortex ii) anodal stimulation on left dorsolateral prefrontal cortex
IFG stimulation
ACTIVE COMPARATORanodal stimulation of left inferior frontal cortex
DLPFC stimulation
ACTIVE COMPARATORanodal stimulation on left dorsolateral prefrontal cortex
Sham stimulation
SHAM COMPARATORsham stimulation
Interventions
stimulating left inferior frontal cortex with transcranial direct current stimulation for 30 minutes
stimulating left dorsolateral prefrontal cortex with transcranial direct current stimulation for 30 minutes
sham stimulation over both left inferior frontal cortex and dorsolateral prefrontal cortex
Eligibility Criteria
You may qualify if:
- healthy subjects with age over 19 years old
You may not qualify if:
- history of disorders involving central nervous system
- patients with severe medical or psychiatric disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Samsung Medical Center
Seoul, South Korea
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 22, 2018
First Posted
April 3, 2018
Study Start
February 28, 2018
Primary Completion
May 22, 2018
Study Completion
May 22, 2018
Last Updated
September 20, 2019
Record last verified: 2018-03