Endodontic Medications for Irreversible Pulpitis: Articaine or Eugenol?

NCT03472456 | Completed

• 1 other identifier: 6953
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of the study is to determine which of the two commonly used endodontic medications (Eugenol VS Articaine) is most effective in controlling postoperative pain in irreversible pulpitis of the mature permanent tooth in adults. To do so, an assessment of the pain felt by patients will be carried out a few days apart. The supposed results are that the medications are equivalent in terms of effectiveness on the pain, but could then present different economic arguments

Conditions

Pulpitides; Endodontic Inflammation; Toothaches; Operative Dentistry

Outcome Measures

Primary Outcomes (1)

• Pain evolution (decrease or increase the intensity of the pain)

  Evolution of pain (using a score of 0 to 10)

  7 days

Study Arms (2)

Articaïne

Drug: Implementation of a pulp medication in compliance with the dental emergency management protocol: articaïne

Eugénol

Drug: Implementation of a pulp medication in compliance with the dental emergency management protocol: eugenol

Interventions

Implementation of a pulp medication in compliance with the dental emergency management protocol: articaïne DRUG

Implementation of a pulp medication in compliance with the dental emergency management protocol: articaïne

Articaïne

Implementation of a pulp medication in compliance with the dental emergency management protocol: eugenol DRUG

Implementation of a pulp medication in compliance with the dental emergency management protocol: eugenol

Eugénol

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients from the University Hospital (Dental Service) of Strasbourg (HUS)

You may qualify if:

• Adult patient, major, affiliated to a social health insurance scheme
• Patient having agreed to participate in the study
• Urgent consultant patient for irreversible pulpitis
• Patient understanding French

You may not qualify if:

• Refusal of the patient to participate in the study
• Impossibility of performing the surgical procedure
• Impossibility to give the subject information enlightened (difficulty of understanding ...)
• Subject under the protection of justice, or under guardianship
• General contraindication to endodontic treatment in 2 sessions (high risk of infectious endocarditis, for example)
• Chronic intake of analgesic drugs

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Les Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France

Location

MeSH Terms

Conditions

Pulpitis; Toothache

Interventions

Compliance

Condition Hierarchy (Ancestors)

Dental Pulp Diseases; Tooth Diseases; Stomatognathic Diseases; Facial Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Elasticity; Mechanical Phenomena; Physical Phenomena

Study Officials

• Damien OFFNER

  Les Hôpitaux Universitaires de Strasbourg

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 12, 2018
• First Posted: March 21, 2018
• Study Start: March 22, 2018
• Primary Completion: March 22, 2018
• Study Completion: October 24, 2019
• Last Updated: September 17, 2020

Record last verified: 2020-09

Locations

FR (1)