Investigation of the Relationship Between Taste Perception and Caries Activity in School Children

NCT03468946 | Completed DMC

• 1 other identifier: SAG-C-DRP-090414-0077
• Study Type: interventional
• Target: 200
• Locations: 0 countries
• Sites: N/A

Brief Summary

Four basic taste perceptions and relationship with caries are poorly investigated in children as compared to adults. The aim of this study was to evaluate salty, sweet, bitter and sour taste perceptions of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors.

Conditions

Healthy

Keywords

taste perception; caries risk; cariogram; children

Outcome Measures

Primary Outcomes (1)

• DMFT, DMFS, dft and dfs indices

  DMFT, DMFS, dft and dfs indices are total counts of decayed, missing, filled teeth / DMFT, Plaque index, Salivary flow rate, buffer capacity, mutans streptococci and lactobacilli counts are combined to report caries risk in high/medium/low caries risk

  1 year

Secondary Outcomes (4)

• Sillness&Löe Index

  1 year

• Salivary flow rate

  1 year

• buffer capacity

  1 year

• mutans streptococci and lactobacilli counts

  1 year

Study Arms (3)

high caries risk

OTHER

children with high caries -identified by cariogram to evaluate sweet taste perception, salty taste perception, sour taste perception and bitter taste perception of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors.

Other: salty taste perception; Other: bitter taste perception; Other: sour taste perception; Other: sweet taste perception

medium caries risk

OTHER

children with medium caries- identified by cariogram to evaluate sweet taste perception, salty taste perception, sour taste perception and bitter taste perception of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors.

Other: salty taste perception; Other: bitter taste perception; Other: sour taste perception; Other: sweet taste perception

low risk

OTHER

no caries or low risk- identified by cariogram to evaluate sweet taste perception, salty taste perception, sour taste perception and bitter taste perception of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors.

Other: salty taste perception; Other: bitter taste perception; Other: sour taste perception; Other: sweet taste perception

Interventions

salty taste perception OTHER

salty taste perception in high caries risk, medium caries risk, low caries risk. The aim of this study was to evaluate salty taste perceptions of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors(high caries risk, medium caries risk, low risk ).

Also known as: sodium chloride, Sigma-Aldrich, USA, RIEDEL SK.S.314

high caries risk; low risk; medium caries risk

bitter taste perception OTHER

bitter taste perception in high caries risk, medium caries risk, low caries risk. The aim of this study was to evaluate bitter taste perceptions of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors (high caries risk, medium caries risk, low risk ).

Also known as: caffeine, Merck, Germany, MERCK 102584

high caries risk; low risk; medium caries risk

sour taste perception OTHER

sour taste perception in high caries risk, medium caries risk, low caries risk. The aim of this study was to evaluate sour taste perceptions of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors (high caries risk, medium caries risk, low risk ).

Also known as: citric acid, Sigma-Aldrich, USA, RIEDEL SK.R.2 7102

high caries risk; low risk; medium caries risk

sweet taste perception OTHER

sweet taste perception in high caries risk, medium caries risk, low caries risk. The aim of this study was to evaluate sweet taste perceptions of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors (high caries risk, medium caries risk, low risk ).

Also known as: sucrose, Merck, Germany, MERCK 1.07651.1 000

high caries risk; low risk; medium caries risk

Eligibility Criteria

• Age: 6 Years - 13 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• \- without any chronic disease such as diabetes and being ASA I or ASA II. We only included patients who had no antibiotics and drug intake within the last month.

You may not qualify if:

• \- chronic disease ASA III, IV antibiotic and drug intake within the last month

Sponsors & Collaborators

• University of Beykent: lead

MeSH Terms

Interventions

Sodium Chloride; Caffeine; Citric Acid; Candy; Sucrose

Intervention Hierarchy (Ancestors)

Chlorides; Hydrochloric Acid; Chlorine Compounds; Inorganic Chemicals; Sodium Compounds; Xanthines; Alkaloids; Heterocyclic Compounds; Purinones; Purines; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, Fused-Ring; Citrates; Tricarboxylic Acids; Acids, Acyclic; Carboxylic Acids; Organic Chemicals; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages; Disaccharides; Oligosaccharides; Polysaccharides; Carbohydrates; Sugars

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: February 19, 2018
• First Posted: March 19, 2018
• Study Start: May 2, 2013
• Primary Completion: May 1, 2014
• Study Completion: December 1, 2014
• Last Updated: March 19, 2018

Record last verified: 2018-03

Data Sharing

• IPD Sharing: Will not share