NCT02241850

Brief Summary

The objective of the study is to investigate the effect of high intensity training on maximal oxygen uptake according to the genetic polymorphisms in healthy Korean volunteers.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
110

participants targeted

Target at P75+ for not_applicable healthy

Timeline
Completed

Started Aug 2013

Typical duration for not_applicable healthy

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2013

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2014

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2014

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 1, 2014

Completed
15 days until next milestone

First Posted

Study publicly available on registry

September 16, 2014

Completed
Last Updated

September 16, 2014

Status Verified

September 1, 2014

Enrollment Period

10 months

First QC Date

September 1, 2014

Last Update Submit

September 14, 2014

Conditions

Healthy

Keywords

High Intensity TrainingGenetic PolymorphismsGenome Wide association studySingle Nucleotide Polymorphism genotypeSubjects

Outcome Measures

Primary Outcomes (1)

  • Change of maximal oxygen uptake

    Baseline and after 6, 9 weeks of training

Study Arms (1)

High intensity training

OTHER

9 weeks of supervised training

Other: High intensity training

Interventions

High intensity trainingOTHER

9 weeks of supervised high intensity training

High intensity training

Eligibility Criteria

Age30 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Age between 30 to 60, healthy male subjects (at screening)
  • Volunteer who totally understands the progress of this clinical trials, make decision by his free will, and signed a consent form to follow the progress.

You may not qualify if:

  • Volunteer who has past or present history of any diseases following below; liver including hepatitis virus carrier, kidney, Neurology, immunology, pulmonary, endocrine, hematooncology, cardiology, mental disorder
  • Subject who already participated in other trials in 30 days
  • Subject who had whole blood donation in 2 months, or component blood donation in 1 months or transfusion
  • Subject who smokes an average of 20 cigarettes/day or drink \> 5 cups of coffee

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Yoo J, Kim BH, Kim SH, Kim Y, Yim SV. Genetic polymorphisms to predict gains in maximal O2 uptake and knee peak torque after a high intensity training program in humans. Eur J Appl Physiol. 2016 May;116(5):947-57. doi: 10.1007/s00421-016-3353-7. Epub 2016 Mar 21.

    PMID: 27001664DERIVED

MeSH Terms

Interventions

High-Intensity Interval Training

Intervention Hierarchy (Ancestors)

Physical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Sung-Vin Yim, MD, PhD

    Kyung Hee University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
M.D., Ph.D.

Study Record Dates

First Submitted

September 1, 2014

First Posted

September 16, 2014

Study Start

August 1, 2013

Primary Completion

June 1, 2014

Study Completion

August 1, 2014

Last Updated

September 16, 2014

Record last verified: 2014-09