Head Mount Display-based Virtual Reality Rehabilitation of Hemispatial Neglect

NCT03463122 | Completed

• 1 other identifier: NRC-2014-04-022
• Study Type: interventional
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

Head-mounted display based virtual reality rehabilitation for hemispatial neglect.

Conditions

Stroke; Neglect, Hemispatial

Keywords

stroke; neglect; virtual reality; head mount display; rehabilitation

Outcome Measures

Primary Outcomes (3)

• Change in Field of regard-response time

  time interval between target onset and response with field of regard setting

  Baseline, 4 weeks from baseline, 8 weeks from baseline

• Change in Field of regard-success rate

  percentage of correct responses (clicking the left or right mouse button in response to a blue or red target, respectively) with field of regard setting

  Baseline, 4 weeks from baseline, 8 weeks from baseline

• Change in Field of regard-head movement

  sum of all quantified head-rotations with field of regard setting

  Baseline, 4 weeks from baseline, 8 weeks from baseline

Secondary Outcomes (5)

• Field of view-response time

  Baseline, 4 weeks from baseline, 8 weeks from baseline

• Field of view-success rate

  Baseline, 4 weeks from baseline, 8 weeks from baseline

• Line bisection test

  Baseline, 4 weeks from baseline, 8 weeks from baseline

• Star cancellation test

  Baseline, 4 weeks from baseline, 8 weeks from baseline

• Catherine Bergego Scale

  Baseline, 4 weeks from baseline, 8 weeks from baseline

Study Arms (2)

Training first

OTHER

This group completed 20 sessions of a field of regard-focused visual exploration therapy program using an head mount display (five daily sessions per week over a period of four weeks) in addition to conventional therapy followed by four weeks of conventional therapy

Device: field of regard-focused visual exploration therapy; Other: conventional therapy

Waiting first

OTHER

This group completed four weeks of conventional therapy followed by 20 sessions of a field of regard-focused visual exploration therapy program using an head mount display (five daily sessions per week over a period of four weeks) in addition to conventional therapy.

Device: field of regard-focused visual exploration therapy; Other: conventional therapy

Interventions

field of regard-focused visual exploration therapy DEVICE

field of regard-focused visual exploration therapy in addition to conventional therapy

Also known as: head mount display

Training first; Waiting first

conventional therapy OTHER

conventional therapy for stroke rehabilitation

Training first; Waiting first

Eligibility Criteria

• Age: 19 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• presence of left hemispatial neglect as demonstrated by a score above the cut-off on the line bisection test or star cancellation test of the Behavioral Inattention Test, or mild-to-moderate neglect-related functional impairment defined by a score of 1-20 points on the Catherine Bergego Scale
• age 19 to 65 years
• first-time right hemispheric ischemic or haemorrhagic stroke as evidenced by brain imaging and medical records
• a score \>25 on the Mini-Mental State Examination

You may not qualify if:

• presence of oculomotor palsies or visual defects as assessed via standard neurological examination
• orthopaedic disorders affecting neck movement
• inability to maintain a seated position.

Sponsors & Collaborators

• National Rehabilitation Center, Seoul, Korea: lead
• Hanyang University: collaborator

Study Sites (1)

National Rehabilitation Center

Seoul, 01022, South Korea

Location

Related Publications (2)

• Shin JH, Kim M, Lee JY, Kim MY, Jeon YJ, Kim K. Feasibility of hemispatial neglect rehabilitation with virtual reality-based visual exploration therapy among patients with stroke: randomised controlled trial. Front Neurosci. 2023 Apr 20;17:1142663. doi: 10.3389/fnins.2023.1142663. eCollection 2023.

  PMID: 37152602 DERIVED

• Kim TL, Kim K, Choi C, Lee JY, Shin JH. FOPR test: a virtual reality-based technique to assess field of perception and field of regard in hemispatial neglect. J Neuroeng Rehabil. 2021 Feb 18;18(1):39. doi: 10.1186/s12984-021-00835-1.

  PMID: 33602254 DERIVED

MeSH Terms

Conditions

Stroke; Perceptual Disorders

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Neurobehavioral Manifestations; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Joon-Ho Shin

  National Rehabilitation Center of Korea

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Team manager of Department of Neurorehabilitation

Study Record Dates

• First Submitted: March 5, 2018
• First Posted: March 13, 2018
• Study Start: August 1, 2014
• Primary Completion: October 30, 2016
• Study Completion: December 31, 2016
• Last Updated: March 13, 2018

Record last verified: 2018-03

Locations

KR (1)