NCT03449095

Brief Summary

In this study, the investigators examine whether emotional and social reward from alcohol varies depending on the social context of consumption.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
640

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 4, 2017

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

November 23, 2017

Completed
3 months until next milestone

First Posted

Study publicly available on registry

February 28, 2018

Completed
5.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 5, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 5, 2023

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

July 31, 2024

Completed
Last Updated

July 31, 2024

Status Verified

July 1, 2024

Enrollment Period

5.7 years

First QC Date

November 23, 2017

Results QC Date

April 27, 2024

Last Update Submit

July 3, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • Self-Reported Emotion

    Positive and negative emotion will be assessed during the laboratory beverage-administration session via self-report on the "8-item Mood Measure." This measure yields two subscales (positive emotion; negative emotion) each ranges from 1 to 6. For positive mood, higher value represents increased alcohol reward. For negative mood, lower value represents increased alcohol reward.

    during the laboratory session, up to 9 hours

  • Self-Reported Social Reinforcement

    Social reinforcement will be assessed using an index of perceived social closeness as well as a modified version of the Perceived Group Reinforcement Scale. The score of the scale ranges from 1 to 9. Higher score indicates increased alcohol reward.

    during the laboratory session, up to 9 hours

Secondary Outcomes (4)

  • Social Bonding

    1 day (laboratory session)

  • Self-Reported Emotion

    2-3 week ambulatory assessment period

  • Interpersonal Distance

    1 day (laboratory session)

  • Neuro-cognitive Social Engagement

    1 day (laboratory session)

Study Arms (2)

Alcohol Administration

EXPERIMENTAL

A moderate dose of alcohol (Target BAC .08%)

Drug: Alcohol

Control Beverage Administration

NO INTERVENTION

Participants consume a non-alcoholic beverage

Interventions

Alcohol Target BAC .08%

Alcohol Administration

Eligibility Criteria

Age21 Years - 30 Years
Sexall(Gender-based eligibility)
Gender Eligibility DetailsMay be either male or female, but must be same as gender assigned at birth.
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Between the ages of 21 and 30
  • Currently drinks alcohol
  • Able to provide at least 2 same-gender friend referrals

You may not qualify if:

  • Female participant is pregnant or trying to become pregnant
  • Endorsed medical disorder caused by, or made worse by, alcohol
  • History of severe alcohol problems
  • Use of drugs known to interact with alcohol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Illinois at Urbana-Champaign

Champaign, Illinois, 61820, United States

Location

Related Publications (5)

  • Steele CM, Josephs RA. Alcohol myopia. Its prized and dangerous effects. Am Psychol. 1990 Aug;45(8):921-33. doi: 10.1037//0003-066x.45.8.921.

    PMID: 2221564BACKGROUND
  • Fairbairn CE. Drinking among strangers: A meta-analysis examining familiarity as a moderator of alcohol's rewarding effects. Psychol Addict Behav. 2017 May;31(3):255-264. doi: 10.1037/adb0000264. Epub 2017 Mar 13.

    PMID: 28287750BACKGROUND
  • Fairbairn CE, Sayette MA. A social-attributional analysis of alcohol response. Psychol Bull. 2014 Sep;140(5):1361-82. doi: 10.1037/a0037563.

    PMID: 25180806BACKGROUND
  • Sayette MA, Creswell KG, Dimoff JD, Fairbairn CE, Cohn JF, Heckman BW, Kirchner TR, Levine JM, Moreland RL. Alcohol and group formation: a multimodal investigation of the effects of alcohol on emotion and social bonding. Psychol Sci. 2012 Aug 1;23(8):869-78. doi: 10.1177/0956797611435134. Epub 2012 Jul 3.

    PMID: 22760882BACKGROUND
  • Fairbairn CE, Sayette MA. The effect of alcohol on emotional inertia: a test of alcohol myopia. J Abnorm Psychol. 2013 Aug;122(3):770-81. doi: 10.1037/a0032980.

    PMID: 24016015BACKGROUND

MeSH Terms

Conditions

Alcohol DrinkingAlcoholismAlcoholic IntoxicationBinge Drinking

Interventions

Ethanol

Condition Hierarchy (Ancestors)

Drinking BehaviorBehaviorAlcohol-Related DisordersSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

AlcoholsOrganic Chemicals

Results Point of Contact

Title
Dr. Catharine Fairbairn
Organization
University of Illinois at Urbana-Champaign

Study Officials

  • Catharine E Fairbairn, Ph.D.

    University of Illinois at Urbana-Champaign

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

November 23, 2017

First Posted

February 28, 2018

Study Start

November 4, 2017

Primary Completion

July 5, 2023

Study Completion

July 5, 2023

Last Updated

July 31, 2024

Results First Posted

July 31, 2024

Record last verified: 2024-07

Locations