Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study

NCT06687525 | Active Not Recruiting

• 1 other identifier: 2R01AA025969
• Study Type: observational
• Target: 240
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, the investigators aim to capture inter- and intra-brain mechanisms underlying alcohol reward in novel social context.

Conditions

Alcohol Drinking; Alcohol Use Disorder; Alcohol Intoxication; Alcohol; Harmful Use; Alcoholism; Binge Drinking

Outcome Measures

Primary Outcomes (4)

• Inter-brain entrainment

  The association between dyad-members EEG signals during the hyperscanning task

  During active laboratory beverage manipulation exposure (during or immediately after beverage administration, at which time participants in the alcohol condition will register a positive BAC)

• Feedback-related negativity

  An ERP component calculated from a time-estimation task

  During active laboratory beverage manipulation exposure (during or immediately after beverage administration, at which time participants in the alcohol condition will register a positive BAC)

• Ambulatory Drinking

  Drinking behavior assessed outside the laboratory using ambulatory assessment

  14 days

• Longitudinal Drinking Problems

  Drinking assessed at longitudinal follow-up

  Up to 24 months post-baseline

Eligibility Criteria

• Age: 21 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Healthy regular drinkers aged 21-30

You may qualify if:

• Between the ages of 21 and 30
• Regularly consumes alcohol

You may not qualify if:

• History of adverse reaction to the amount of beverage employed in the study
• Have a history of major problems associated with alcohol
• Take medications that could adversely interact with alcohol
• Have medical conditions that contraindicate alcohol administration
• Individuals with a history of skull fractures or who indicate discomfort with EEG procedures used
• Female participant is pregnant or trying to become pregnant

Sponsors & Collaborators

• University of Illinois at Urbana-Champaign: lead

Study Sites (1)

University of Illinois at Urbana-Champaign

Champaign, Illinois, 61820, United States

Location

Related Publications (3)

• Sayette MA, Creswell KG, Dimoff JD, Fairbairn CE, Cohn JF, Heckman BW, Kirchner TR, Levine JM, Moreland RL. Alcohol and group formation: a multimodal investigation of the effects of alcohol on emotion and social bonding. Psychol Sci. 2012 Aug 1;23(8):869-78. doi: 10.1177/0956797611435134. Epub 2012 Jul 3.

  PMID: 22760882 BACKGROUND

• Fairbairn CE, Sayette MA. A social-attributional analysis of alcohol response. Psychol Bull. 2014 Sep;140(5):1361-82. doi: 10.1037/a0037563.

  PMID: 25180806 BACKGROUND

• Fairbairn CE, Kang D, Federmeier KD. Alcohol and Neural Dynamics: A Meta-analysis of Acute Alcohol Effects on Event-Related Brain Potentials. Biol Psychiatry. 2021 May 15;89(10):990-1000. doi: 10.1016/j.biopsych.2020.11.024. Epub 2020 Dec 11.

  PMID: 33579536 BACKGROUND

MeSH Terms

Conditions

Alcohol Drinking; Alcoholism; Alcoholic Intoxication; Binge Drinking

Condition Hierarchy (Ancestors)

Drinking Behavior; Behavior; Alcohol-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders

Study Officials

• Catharine E Fairbairn, Ph.D.

  University of Illinois at Urbana-Champaign

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 26, 2024
• First Posted: November 13, 2024
• Study Start: April 5, 2024
• Primary Completion: January 26, 2026
• Study Completion (Estimated): June 1, 2028
• Last Updated: May 4, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will share

Locations

US (1)