NCT03442439

Brief Summary

The purpose of this current study is to investigate the efficacy of a group model of Family Nurture Intervention in ameliorating behavioral problems in preschool-aged children. The behavioral, neurobiological and clinical insights gained from this project may eventually lead to better treatment of emotional, behavioral, and developmental disorders. The investigator hypothesizes that the children who are treated with Family Nurture Intervention (FNI), which incorporates interactive touch with vocal soothing, and family practice in comforting, will show increased emotional connection and mother child co-regulation with better results in the outcome measures in the short term and long term.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 31, 2018

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

February 2, 2018

Completed
20 days until next milestone

First Posted

Study publicly available on registry

February 22, 2018

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 25, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 25, 2018

Completed
Last Updated

April 8, 2019

Status Verified

April 1, 2019

Enrollment Period

10 months

First QC Date

February 2, 2018

Last Update Submit

April 4, 2019

Conditions

Keywords

Family Nurture InterventionMartha G. Welch MDRandomized Controlled TrialPreschool InterventionPre-school InterventionMultiple Family Group InterventionEmotional ConnectionCo-regulation

Outcome Measures

Primary Outcomes (1)

  • Welch Emotional Connection Scale (WECS) Score

    This is designed to measure emotional connection. Children will be asked to sit on their mother's lap for five minutes. This interaction will be video taped, and will be behaviorally coded using the Welch Emotional Connection Scale (WECS) and using a paradigm evaluated in Noldus coding software. The Welch Emotional Connection Scale (WECS) construct is emotional connection between mother and child, which we hypothesize predicts optimal development. There are four items on the WECS: Mutual Attraction, Mutual Vocal Exchange, Mutual Facial Engagement, and Mutual Sensitivity/Reciprocity. Each item is rated on a scale from 1 to 3 in 0.25 increments with a score of 3 considered optimal. At or below 2.25 on any individual item, or a total score below 9 means that the mother-child pair is not emotionally connected. There is also a binary question to the rater asking if the pair is emotionally connected - yes or no. The mother and child are scored as a pair, not individually.

    12 months

Study Arms (2)

Nutrition and Play Intervention (NPI)

ACTIVE COMPARATOR

Half of the mother-child dyads who are enrolled into the study will be randomly assigned to the Nutrition and Play Intervention group.

Behavioral: Nutrition and Play Intervention

Family Nurture Intervention (FNI)

EXPERIMENTAL

Half of the mother-child dyads who are enrolled into the study will be randomly assigned to the Family Nurture Intervention group.

Behavioral: Family Nurture Intervention

Interventions

Mothers and children in the Nutrition and Play group will play educational and nutrition-focused games.

Also known as: NPI
Nutrition and Play Intervention (NPI)

The mother-child pair will be asked to talk and play with each other as they customarily do. If the child becomes restless and dysregulated the mother will be coached by the Nurture Specialist to bring the child back into a calm state though sustained physical contact; comfort touch, soothing words, and eye contact.

Also known as: FNI
Family Nurture Intervention (FNI)

Eligibility Criteria

Age24 Months - 54 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Child is a singleton
  • Mother can speak, read and write in English or Spanish
  • Child is between the ages of 2-4 1/2 years at date of enrollment
  • Mother is 18 years of age or older at the time of consent
  • Child resides with mother
  • Child demonstrates developmental deficit as measured by the Strengths and Difficulties Questionnaire (13 or higher on behavioral questions or 4 or less on prosocial questions)
  • Mother and child deemed "emotionally unconnected" using the Welch Emotional Connection Scale (WECS) to score their five minute Welch Lap Test video
  • Mother is able to commit to study schedule

You may not qualify if:

  • The child has severe congenital anomalies or chromosomal anomalies including Downs syndrome and Cerebral palsy
  • Child has a motor disability
  • Mother sees or hears things that other people do not seem to see or hear
  • Mother has trouble distinguishing whether something is real or part of imagination or dreams
  • Mother is currently taking antipsychotic medications
  • Mother or child have any medical conditions that might prevent them from participating in block play, mother holding child, or child sitting on mother's lap
  • Mother has any current drug and/or alcohol abuse
  • Mother is more than 4 months pregnant
  • Mother is currently involved with Department of Children and Families
  • The child has a diagnosis of Autism

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stamford Childrens Learning Center

Stamford, Connecticut, 06902, United States

Location

MeSH Terms

Conditions

Mental DisordersLearning DisabilitiesAffective Symptoms

Interventions

Nutritional Status

Condition Hierarchy (Ancestors)

Communication DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsNeurodevelopmental DisordersBehavioral SymptomsBehavior

Intervention Hierarchy (Ancestors)

Nutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological PhenomenaHealth StatusDemographyPopulation Characteristics

Study Officials

  • Martha G Welch, MD

    Columbia University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor of Psychiatry (in Pediatrics and Pathology and Cell Biology)

Study Record Dates

First Submitted

February 2, 2018

First Posted

February 22, 2018

Study Start

January 31, 2018

Primary Completion

November 25, 2018

Study Completion

November 25, 2018

Last Updated

April 8, 2019

Record last verified: 2019-04

Locations