NCT02717390

Brief Summary

The Investigators propose to conduct a pragmatic randomized controlled trial of 350 one to four year old children and their caregivers to study the effectiveness of 1) the Bright By Three (BB3) intervention for promoting children's language and socio-emotional development and 2) a modified version of the Safe 'N Sound (SNS) intervention for reducing safety hazards and injuries. The SNS intervention will serve as a control for the BB3 group and vice versa so that all study participants will receive a clinically meaningful intervention. In collaboration with primary care clinics that serve low-income and minority children, the Investigators will recruit and randomize 350 twelve to fifteen month olds and their parents/caregivers to one of the two intervention arms and deliver the interventions over a 2 year period.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2017

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 15, 2016

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 23, 2016

Completed
1.4 years until next milestone

Study Start

First participant enrolled

August 1, 2017

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 30, 2019

Completed
Last Updated

November 4, 2020

Status Verified

November 1, 2020

Enrollment Period

1.7 years

First QC Date

March 15, 2016

Last Update Submit

November 2, 2020

Conditions

Keywords

ReadingEarly Childhood developmentTalkingPlayingPraisingSafetyInjury prevention

Outcome Measures

Primary Outcomes (3)

  • Change in parental behavior based on the Stim-Q

    The Stim-Q assessment tool is a reliable and valid of the cognitive stimulation provided in the home for children between 5 months and 6 years old. It can be completed by a parent in English or Spanish in about 20 minutes and has been used in several studies of interventions to support early childhood development

    Child ages 1, 2, 3 and 4

  • Change in children's language development based on the CDI

    The MacArthur-Bates Communicative Development Inventories (CDI)-Words and Gestures, Words and Sentences, and CDI-III forms are norm- referenced measures of children's language development that can be completed by a parent in English or Spanish in about 20 minutes for children 8 through 37 months of age.

    Child ages 1 and 2.

  • Change in children's language development based on the E/ROWPVT-4

    The Receptive and Expressive One- Word Picture Vocabulary Tests (E/ROWPVT-4) are norm-referenced assessments used to assess receptive and expressive vocabulary skills in children ages 2 years and older who speak English or Spanish. These tests can be administered in-person by a trained research assistant and each take about 20 minutes to complete. Both the CDI and the E/ROWPVT have been used in studies of interventions for language development.

    Child age 3.

Secondary Outcomes (3)

  • Parental attitudes, norms, self-efficacy, and intentions toward talking, reading, playing, praising (TRPP) behaviors

    Child ages 1, 2 and 3

  • Parental positive regard for the children measured by the Parenting Stress Index

    Child ages 1, 2 and 3

  • Children's socio-emotional development based on the Child Behavior Checklist

    Child ages 2 and 3

Study Arms (2)

Bright By Three (BB3) Intervention

EXPERIMENTAL

The purpose of the BB3 intervention (annual home visit, written materials, and BB3 mobile application 'app') is to increase parental talking, reading, playing, and praise (TRPP) behaviors and improves children's social-emotional and language development at ages 2, 3, and 4 years

Behavioral: Bright By Three (BB3)

Texts for Child Safety (TCS) Intervention

ACTIVE COMPARATOR

The purpose of the injury prevention arm is to reduce the prevalence of safety hazards in the home and car environments, decrease the number of self-reported and medically-attended injuries among children, and increase caregiver's self-reported safety behaviors and knowledge of child safety. The Investigators will compare the results of our tailored child safety intervention (Texts for Child Safety \[TCS\]) among participants in the injury prevention arm with those randomized to the BB3 arm.

Behavioral: Texts for Child Safety (TCS)

Interventions

The purpose of the BB3 intervention (annual home visit, written materials, and BB3 mobile application 'app') is to increase parental talking, reading, playing, and praise (TRPP) behaviors and improves children's social-emotional and language development at ages 2, 3, and 4 years.

Bright By Three (BB3) Intervention

The purpose of the injury prevention arm is to reduce the prevalence of safety hazards in the home and car environments, decrease the number of self-reported and medically-attended injuries among children, and increase caregiver's self-reported safety behaviors and knowledge of child safety. The Investigators will compare the results of our tailored child safety intervention (Texts for Child Safety \[TCS\]) among participants in the injury prevention arm with those randomized to the BB3 arm.

Texts for Child Safety (TCS) Intervention

Eligibility Criteria

Age12 Months - 15 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Low-income (based on insurance status of child being Medicaid or CHIP),
  • Lower educational level (less than college level education) parents of 12 to 15 month old children from the Rocky Mountain Youth Clinic and the Child Health Clinic who speak either English or Spanish or both and their 12-15 month old toddlers.

You may not qualify if:

  • Parents with children born prior to 36 weeks gestation (premature infants)
  • Children with chronic conditions known to affect neuro-development, such as trisomy 21, or
  • Children who have a positive screen on the Children with Special Health Care Needs screener 57
  • Parents who have already participated in the BB3 program
  • Parents without access to a smart phone
  • Parents who cannot read or converse in either English or Spanish

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Colorado AMC

Aurora, Colorado, 80045, United States

Location

Related Publications (1)

  • Cunningham MA, Gorman C, McNulty MC, Chavez C, Luna-Asturias C, Dixon CA, Bull S, Berman S, Allison MA. Engage, Develop, Learn: a pilot randomized clinical trial to test if a mobile application can enhance home support for early cognitive development among children living in poverty. Mhealth. 2023 Jan 28;9:4. doi: 10.21037/mhealth-22-13. eCollection 2023.

MeSH Terms

Conditions

Learning DisabilitiesSpeech

Interventions

bombesin receptor subtype 3

Condition Hierarchy (Ancestors)

Communication DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsNeurodevelopmental DisordersMental DisordersVerbal BehaviorCommunicationBehavior

Study Officials

  • Mandy Allison, MD, MSPH

    University of Colorado, Denver

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 15, 2016

First Posted

March 23, 2016

Study Start

August 1, 2017

Primary Completion

March 30, 2019

Study Completion

March 30, 2019

Last Updated

November 4, 2020

Record last verified: 2020-11

Locations