Recollect the Game: A Novel Treatment for Executive Functioning Deficits in Adults With ADHD

NCT03437993 | Unknown

• 1 other identifier: Recollect_ADHD
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Adults who have attention deficit hyperactivity disorder (ADHD) suffer from significant occupational, academic and social problems, many of which are believed to be a result of problems with executive functioning. Executive functioning refers to a group of neuro-psychological functions which include sustained attention, working memory, verbal fluency, as well as motor and mental processing speed. Individuals with ADHD have been shown to have deficits in executive functioning independent of IQ, co-occurring psychiatric disorders, gender, and ADHD subtype. "Recollect" is an application (App) based working memory training video game where participants conduct 3-different adaptive working memory tasks. In each of these tasks participants are presented with a set of stimuli to be remembered while playing a simple platform game where they help navigate an astronaut across the screen and dodge obstacles. Recollect has been designed for all age groups to an interesting, fun and effective brain-training activity. The memory tasks included in the game have been independently shown to improve working memory in a manner that transfers to untrained tasks. The purpose of this study is to evaluate the effects of playing Recollect versus Tetris for 20 minutes per day, 5 days per week over a 4 week period, on executive functioning deficits in individuals who have Adult ADHD.

Conditions

Adult ADHD

Keywords

ADHD; executive functioning; game

Outcome Measures

Primary Outcomes (1)

• Change from baseline on The Behavioral Rating Inventory of Executive Functioning - Adult Version (BRIEF-A)

  It is a validated, clinician-rated scale, measuring executive functioning. The scale includes 75 items that rates patient symptoms on a 3-point Likert scale (1 = behavior is never observed to 3 = behavior is often observed). Scores range from 75 to 225: Higher scores indicate greater impairment in executive functioning.

  Change from baseline to week 4

Secondary Outcomes (2)

• Change from baseline on the Barkley Adult ADHD Rating Scale (BAARS-IV)

  Change from baseline to week 4

• Change from baseline on an App-based neuro-cognitive battery

  Change from baseline to week 4

Study Arms (2)

Recollect

EXPERIMENTAL

Recollect is a video game which incorporates scientifically supported renditions of N-Back, Item Span, and Multiple-Identity tracking tasks. These tasks are independently shown to improve working memory in a manner that transfers to untrained tasks.

Other: Recollect, the game

Tetris

SHAM COMPARATOR

Tetris is a video game which has not been shown to have any benefits in the improvement of executive functioning.

Other: Tetris

Interventions

Recollect, the game OTHER

"Recollect" is a working memory training game

Recollect

Tetris OTHER

App-based video game where shapes are rotated and placed to fit a grid

Tetris

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Males and females aged 18 and older who own a mobile device such as a Smartphone or tablet.
• Current diagnosis of Adult ADHD, at any stage of treatment.
• Comorbid psychiatric conditions will be allowed.
• Medication or psychotherapy must have been stable (no dose changes) for 4 weeks prior to study participation.
• Must be able to read, write and understand English.

You may not qualify if:

• Participant does not own a Smartphone or tablet.
• No dose changes during the 4 week study period.
• No initiation of new psychological therapy or counselling during the 4 week study period.

Sponsors & Collaborators

• McMaster University: lead

Study Sites (1)

MacAnxiety Research Centre

Hamilton, Ontario, L8S 1B7, Canada

Location

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior Disorders; Neurodevelopmental Disorders; Mental Disorders

Study Officials

• Michael Van Ameringen, MD, FRCPC

  McMaster University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 7, 2018
• First Posted: February 19, 2018
• Study Start: March 14, 2019
• Primary Completion: December 31, 2024
• Study Completion: February 28, 2025
• Last Updated: October 26, 2023

Record last verified: 2023-10

Locations

CA (1)