NCT02728011

Brief Summary

The purpose of this study was to examine the feasibility and efficacy of computerized cognitive exercises from Scientific Brain Training (SBT), compared to the computer game Tetris as an active placebo, in a pilot study of adolescents with Attention-deficit/hyperactivity disorder (ADHD).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2010

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2010

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2010

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
4.3 years until next milestone

First Submitted

Initial submission to the registry

March 24, 2016

Completed
12 days until next milestone

First Posted

Study publicly available on registry

April 5, 2016

Completed
Last Updated

April 5, 2016

Status Verified

March 1, 2016

Enrollment Period

2 months

First QC Date

March 24, 2016

Last Update Submit

April 4, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Activity Perception Questionnaire

    7 weeks

Secondary Outcomes (4)

  • Attention Deficit/Hyperactivity Disorder-Rating Scale

    7 weeks

  • Cambridge Neuropsychological Test Automated Battery (CANTAB) Rapid Visual Information Processing (RVP)(A)

    7 weeks

  • CANTAB: Stockings of Cambridge (SOC) (problems solved in minimum moves)

    7 weeks

  • CANTAB: DMS Delayed Matching to Sample (DMS)

    7 weeks

Other Outcomes (4)

  • CANTAB: Spatial Span (SSP)

    7 weeks

  • CANTAB: Intra-Extra Dimensional Set Shift (IED)

    7 weeks

  • CANTAB: Spatial Working Memory (SWM)

    7 weeks

  • +1 more other outcomes

Study Arms (2)

Intervention

EXPERIMENTAL

Scientific Brain Training (SBT)

Other: Scientific Brain Training (SBT)

Controle

PLACEBO COMPARATOR

Tetris

Other: Tetris

Interventions

Cognitive training

Intervention
TetrisOTHER
Controle

Eligibility Criteria

Age14 Years - 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • a clinical diagnosis of hyperkinetic disorder (F90.0, corresponding to ADHD combined type) (WHO, 1993);
  • age between 14-17 years;
  • IQ \> 80.

You may not qualify if:

  • pharmacological treatment other than methylphenidate, dexamphetamine and/or atomoxetine;
  • comorbid conduct disorder, autism spectrum disorders or major depression;
  • history of head trauma or verified neurological disease;
  • motor or perceptual disabilities which prevented the use of a computer;
  • medical illness that required treatment;
  • no access to a computer and internet at home.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Child and Adolescent Mental Health Services Aabenraa

Aabenraa, 6200, Denmark

Location

Child and Adolescent Mental Health Services Augustenborg

Augustenborg, 6440, Denmark

Location

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior DisordersNeurodevelopmental DisordersMental Disorders

Study Officials

  • Aida Bikic, MSc

    Region Syddanmark

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
psychologist, ph.d. candidate

Study Record Dates

First Submitted

March 24, 2016

First Posted

April 5, 2016

Study Start

October 1, 2010

Primary Completion

December 1, 2010

Study Completion

December 1, 2011

Last Updated

April 5, 2016

Record last verified: 2016-03

Data Sharing

IPD Sharing
Will share

Locations