NCT03433456

Brief Summary

The purpose of this study is to evaluate whether an intervention targeting healthy habit development reduces the risk and prevalence of obesity in low-income mothers and children. The study intends to evaluate whether the intervention, delivered in the context of home visitation services for low-income families, reduces weight gain and risk factors associated with parent and childhood obesity compared to those receiving standard home visitation services.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
296

participants targeted

Target at P75+ for not_applicable obesity

Timeline
Completed

Started Dec 2019

Longer than P75 for not_applicable obesity

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 31, 2018

Completed
14 days until next milestone

First Posted

Study publicly available on registry

February 14, 2018

Completed
1.8 years until next milestone

Study Start

First participant enrolled

December 2, 2019

Completed
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 27, 2023

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

April 24, 2024

Completed
Same day until next milestone

Results Posted

Study results publicly available

April 24, 2024

Completed
Last Updated

October 29, 2024

Status Verified

October 1, 2024

Enrollment Period

3.2 years

First QC Date

January 31, 2018

Results QC Date

February 23, 2024

Last Update Submit

October 17, 2024

Conditions

Keywords

obesitylow-incomehealth disparitieshome visitationpreventionchildhood obesityhabit

Outcome Measures

Primary Outcomes (2)

  • Weight of Mothers

    Body weight (kg) at baseline and follow-up assessments.

    Baseline, 6 months, 12 months

  • Weight of Children

    Body weight (kg) at baseline and follow-up assessments..

    Baseline, 6 months, 12 months

Secondary Outcomes (3)

  • Habit Strength of Targeted Behaviors

    Baseline, 6 months, 12 months

  • Household Environment Assessing the Number of Different Food Items Available

    Baseline, 6 months, 12 months

  • Household Environment Assessing the Number of Different Activity-promoting Items Available

    Baseline, 6 months, 12 months

Other Outcomes (4)

  • Maternal Eating Practices

    Baseline, 6 months, 12 months

  • Maternal Feeding Practices

    Baseline, 6 months, 12 months

  • Caregiver Depressive Symptoms on the Personal Health Questionnaire Depression Scale (PHQ-8)

    Baseline, 6 months, 12 months

  • +1 more other outcomes

Study Arms (2)

Home visitation + HABITS Program

EXPERIMENTAL

The HABITS module will target 5 key behaviors (physical activity, increasing fruit and vegetable consumption, decreasing sugary beverages, decreasing fried foods, and encouraging regular self-monitoring and self-weighing) aimed at reducing obesity risk in mothers or primary caregivers and children. Participants will receive the HABITS module in addition to their standard home visitation services.

Behavioral: Home visitation + HABITS programBehavioral: Standard home visitation program

Standard home visitation program

ACTIVE COMPARATOR

Participants will receive the standard of care home visitation regularly delivered through the existing home visitation program without the HABITS module.

Behavioral: Standard home visitation program

Interventions

The HABITS program will target 5 key behaviors (physical activity, increasing fruit and vegetable consumption, decreasing sugary beverages, decreasing fried foods, and encouraging regular self-monitoring and self-weighing) aimed at reducing obesity risk in mothers or primary caregivers and children.

Home visitation + HABITS Program

Treatment in the control arm includes the content and services typically provided by the home visitation partner, which is focused on promoting caregiver and child health by providing screenings and referrals, encouraging smoking cessation, promoting safe sleep practices, and strengthening children's school readiness and achievement, social/emotional and physical development.

Home visitation + HABITS ProgramStandard home visitation program

Eligibility Criteria

Age0 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Mothers or Primary Caregivers:
  • Age 18-75 years of age
  • Enrollment in First Teacher Home Visiting Program (First Teacher) through the Family Guidance Center of Alabama.
  • Mother or primary caregiver of 0-4 year old child
  • Generally Healthy
  • Children:
  • years of age at time of enrollment
  • Parent or primary caregiver enrolled in First Teacher

You may not qualify if:

  • Mothers or primary caregivers:
  • Currently enrolled in a diet and weight loss program, AND either a) significant weight loss of 10+ pounds in the last 6 months, OR b) unwilling to discontinue from current diet and weight loss program.
  • Children:
  • Child has a history of a feeding or eating disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Alabama at Birmingham

Birmingham, Alabama, 35205, United States

Location

Related Publications (1)

  • Salvy SJ, Dutton GR, Borgatti A, Kim YI. Habit formation intervention to prevent obesity in low-income preschoolers and their mothers: A randomized controlled trial protocol. Contemp Clin Trials. 2018 Jul;70:88-98. doi: 10.1016/j.cct.2018.05.015. Epub 2018 May 24.

    PMID: 29802965BACKGROUND

MeSH Terms

Conditions

ObesityPediatric ObesityHabits

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsBehavior

Limitations and Caveats

Due to COVID-19, there were protocol changes to the study and no data available for some of the 6-month study visits.

Results Point of Contact

Title
Dr. Gareth Dutton
Organization
University of Alabama at Birmingham

Study Officials

  • Sarah J. Salvy, PhD

    University of Alabama at Birmingham

    PRINCIPAL INVESTIGATOR
  • Gareth R. Dutton, PhD

    University of Alabama at Birmingham

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Caregiver-child dyads will be randomized to either the intervention group (receiving home intervention + HABITS program) or the a control group to receive their standard of care (home intervention without HABITS)
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

January 31, 2018

First Posted

February 14, 2018

Study Start

December 2, 2019

Primary Completion

February 27, 2023

Study Completion

April 24, 2024

Last Updated

October 29, 2024

Results First Posted

April 24, 2024

Record last verified: 2024-10

Data Sharing

IPD Sharing
Will share

With the documented permission of the IRB, the PI may develop a transportable de-identified database, codebook, and mechanism by which data can be shared with qualified investigators. Interested investigators will be asked to complete a standardized request form stating the specific aims of the analyses, the analytic plan, available resources for completing the proposed project, proposed timeline, and goals (i.e., manuscripts, presentations, and/or grant applications). The PI and research team will review these requests to determine whether the proposed analyses constitute an innovative and significant exploration of the data, whether the proposed team has sufficient resources to complete the request, and whether data will be adequately protected and managed. If any of these issues are problematic, the PI and research team will attempt to negotiate a fair resolution with the interested investigators and NIMHD program staff.

Shared Documents
STUDY PROTOCOL, SAP, CSR, ANALYTIC CODE

Locations