Comparing the Impact of Cancer on Quality of Life Between Survivors of Childhood Solid Tumors and Leukemia

NCT03430752 | Completed DMC

• 1 other identifier: UW 17-331 (2)
• Study Type: observational
• Target: 135
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to examine the impact of cancer and treatment-related effects on the physical and psychosocial well-being and quality of life among Hong Kong Chinese survivors of childhood solid tumors.

Conditions

Childhood Solid Tumor

Outcome Measures

Primary Outcomes (1)

• Quality of Life at baseline

  The Pediatric Quality-of-Life Inventory 4.0 Generic core sales (PedsQL 4.0) consists of 23 items which are designed to measure the quality of life in four particular domains including physical ability, psychological states, social relationships and school functioning. PedsQL 4.0 is a five-point Likert scale for patients to response regarding to the experience over the last month. Higher scores represent better quality of life. Participants will be asked to respond to the Pediatric Quality-of-Life Inventory 4.0 Generic core sales (PedsQL 4.0) at baseline.

  Baseline

Secondary Outcomes (4)

• Levels of self-esteem at baseline

  Baseline

• Number of depressive symptoms at baseline

  Baseline

• Level of sense of hope at baseline

  Baseline

• Resilience ability at baseline

  Baseline

Study Arms (2)

Survivors of Childhood Solid Tumors

Survivors of Childhood Solid Tumors were invited to fill in a set of questionnaires.

Other: questionnaires

Survivors of Childhood Leukemia

Survivors of Childhood Leukemia were invited to fill in a set of questionnaires.

Other: questionnaires

Interventions

questionnaires OTHER

Participants were asked to respond to the questionnaires including the Chinese version of the Paediatric Quality of Life Inventory 4.0 Generic Core Scale (PedsQL 4.0), the Chinese version of the Center for Epidemiological Studies Depression Scale for Children (CES-DC), the Chinese version of Rosenberg self-esteem scale, the Chinese version of the Herth Hope Index (HHI) and the Chinese version of Resilience Scale for Children (RS10).

Survivors of Childhood Leukemia; Survivors of Childhood Solid Tumors

Eligibility Criteria

• Age: 6 Years - 19 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Hong Kong Chinese under the age of 19 years who completed the entire course of treatment at least 6 months and were diagnosed with childhood solid tumors or leukemia under the age of 19 years.

You may qualify if:

• (1) Hong Kong Chinese under the age of 30 years at the time of study participation;
• (2) diagnosed with solid tumors or hematological malignancies under the age of 19 years;
• (3) completed the entire course of treatment for at least 6 months;
• (4) able to speak fluent Cantonese and read Chinese.

You may not qualify if:

• Survivors with secondary malignancy, organic cause psychosis, cognitive or learning problems, or under active cancer treatment will be excluded from this study.

Sponsors & Collaborators

• The University of Hong Kong: lead

Study Sites (1)

The University of Hong Kong

Hong Kong, Hong Kong

Location

MeSH Terms

Interventions

Surveys and Questionnaires

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Ho Cheung William Li

  The University of Hong Kong

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 6, 2018
• First Posted: February 13, 2018
• Study Start: September 5, 2017
• Primary Completion: August 31, 2018
• Study Completion: August 31, 2018
• Last Updated: June 28, 2019

Record last verified: 2019-06

Data Sharing

• IPD Sharing: Will not share

Locations

HK (1)