The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors

NCT03298971 | Unknown DMC

• 1 other identifier: UW 17-331
• Study Type: observational
• Target: 240
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to examine the impact of cancer and treatment-related effects on the physical and psychosocial well-being and quality of life among Hong Kong Chinese survivors of childhood osteosarcoma.

Conditions

Childhood Osteosarcoma

Outcome Measures

Primary Outcomes (1)

• Levels of quality of life at baseline

  The quality of life of the participants will be measured by the Hong Kong Chinese Version World Health Organization quality of life measure, abbreviated version (WHOQOL-BREF (HK)). It consists of 28 items with a five-point response Likert scale. There are two questions to access the overall perception of quality of life and health respectively. The remaining 26 items were designed to assess the perception of quality of life in four particular domains including physical health, psychological well-being, social relationships and environments. Higher scores represent higher levels of QoL. Participants will be asked to respond to the Hong Kong Chinese Version World Health Organization quality of life measure, abbreviated version (WHOQOL-BREF (HK)) at baseline.

  baseline

Secondary Outcomes (3)

• Levels of self-esteem at baseline

  baseline

• Number of depressive symptoms at baseline

  baseline

• Level of sense of hope at baseline

  baseline

Study Arms (2)

Survivors of Childhood Osteosarcoma

Survivors of Childhood Osteosarcoma were invited to fill in a set of questionnaires.

Other: Questionnaires

Healthy Subjects

Healthy Subjects were invited to fill in a set of questionnaires.

Other: Questionnaires

Interventions

Questionnaires OTHER

Participants were asked to respond to the questionnaires including Hong Kong Chinese Version World Health Organization quality of life measure, abbreviated version (WHOQOL-BREF (HK)), the Chinese version of The Center for Epidemiological Studies - Depression Scale (CES-D), the Chinese version of Rosenberg self-esteem scale, and the Chinese version of the Herth Hope Index (HHI).

Healthy Subjects; Survivors of Childhood Osteosarcoma

Eligibility Criteria

• Age: Up to 30 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Hong Kong Chinese under the age of 30 years who completed the entire course of treatment at least 5 years and were diagnosed with osteosarcoma under the age of 19 years.

You may qualify if:

• Hong Kong Chinese under the age of 30 years at the time of study participation;
• Diagnosed with osteosarcoma under the age of 19 years;
• Completed the entire course of treatment at least 5 years;
• Able to speak fluent Cantonese and read Chinese.

You may not qualify if:

• Survivors with secondary malignancy, organic cause psychosis, cognitive or learning problems, or under active cancer treatment

Sponsors & Collaborators

• The University of Hong Kong: lead

Study Sites (1)

The University of Hong Kong

Hong Kong, Hong Kong

RECRUITING

MeSH Terms

Interventions

Surveys and Questionnaires

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Ho Cheung William Li

  The University of Hong Kong

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ho Cheung William Li

CONTACT

39176634; william3@hku.hk

Long Kwan Ho

CONTACT

39176643; longkwan@hku.hk

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 27, 2017
• First Posted: October 2, 2017
• Study Start: September 8, 2017
• Primary Completion: December 1, 2022
• Study Completion: December 1, 2022
• Last Updated: September 8, 2021

Record last verified: 2020-11

Data Sharing

• IPD Sharing: Will not share

Locations

HK (1)