The Relationship Between Atrial Fibrillation and Frailty in Community-Dwelling Elderly

NCT03420326 | Completed

• 1 other identifier: 201711083RIND
• Study Type: observational
• Target: 256
• Locations: 1 country
• Sites: 1

Brief Summary

Atrial fibrillation (AF) is the most common arrhythmias in clinical practice. Research investigating hospitalized patients have indicated there are deleterious effects of AF on patients besides the disease burden itself, including longer stay days for hospitalization, higher rates of frailty and increasing mortality rate after discharged in six months. In the community-dwelling research also found that elderly with AF have lower cognitive function, physical functional tests score and slower walking speed compared with the health ones. However, there is limited articles investigating the impact of AF on community-dwelling elderly, and the relationship between AF and frailty is also lack of discussion. According to the aged society and increasing prevalence of AF, the relationship between AF and frailty in community-dwelling elderly is warranting investigated.

Conditions

Atrial Fibrillation; Frail Elderly Syndrome

Keywords

Atrial Fibrillation; Frailty status; Body composition; Sarcopenia

Outcome Measures

Primary Outcomes (1)

• Frailty status

  Edmonton frail scale and Frailty criteria by Dr. Fried would be used to evaluate the frail status of the participants

  The frail status assessment would take about 10 minutes

Secondary Outcomes (1)

• Body composition

  The body composition test would take about 10 minutes

Study Arms (2)

Atria fibrillation (AF) group

1. Detection of AF during 30 seconds ECG assessment 2. Once diagnosed with atrial fibrillation before 3. Undergo the frailty status assessment

Behavioral: Frailty status assessment

Non-AF group

1. No detection of AF during 30 seconds ECG assessment 2. Undergo the frailty status assessment

Behavioral: Frailty status assessment

Interventions

Frailty status assessment BEHAVIORAL

The Edmonton frail scale and Frailty criteria by Dr. Fried would be used to assess participants frailty status

Atria fibrillation (AF) group; Non-AF group

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

National Taiwan University Hospital Communities in Taipei city

You may qualify if:

• Older than 65 years old

You may not qualify if:

• diagnosed with the following disease
• Cardiovascular diseases: myocardial infarction, peripheral vascular diseases, aortic plaque
• Cerebrovascular disease: stroke, transient ischemic attack, emboli
• Heart failure
• Participants who cannot finish the trial

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

Ming-Ting Yang

Taipei, Zhongzheng District, 100, Taiwan

Location

MeSH Terms

Conditions

Atrial Fibrillation; Sarcopenia

Condition Hierarchy (Ancestors)

Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Signs and Symptoms

Study Officials

• Meng-Yueh Chien

  College of medicine, National Taiwan University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 25, 2018
• First Posted: February 5, 2018
• Study Start: January 26, 2018
• Primary Completion: June 1, 2018
• Study Completion: June 1, 2018
• Last Updated: March 5, 2019

Record last verified: 2018-01

Locations

TW (1)