Trials Sponsors Conditions Drugs Pricing

Conditions

Siewert Type II Adenocarcinoma of Esophagogastric Junction

Keywords

esophageal canceradenocarcinoma of the esophagusesophageal surgery

Outcome Measures

Primary Outcomes (1)

Survival
5 year survival between intestinal and diffuse types (Lauren's classification) of Siewert type II adenocarcinoma after primary surgery,
5 years

Secondary Outcomes (1)

Frequency of gastric greater curvature lymph nodes metastases in Siewert II adenocarcinoma
5 years

Interventions

Total GastrectomyProcedure

The esophagus was resected at the arch level of the azygos vein, a frozen section of the resection margin was routinely performed to achieve a proximal clean resection margin. The surgical specimen was comprehensive of distal esophagus, stomach and omentum. Digestive tract continuity was established with Roux-en-Y esophagojejunostomy. Lymphadenectomy was extended to the thoracic stations R 2-4, 7-8-9, and L 4, numbered according to the Mountain's classification \[39\] (Suppl. File 2 Figure A) and to the abdominal stations 1-12, numbered according to the Japanese Research Society for Gastric Cancer (JRSGC) 1998 classification.

Also known as: Distal Esophagectomy

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 85 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodProbability Sample

Study Population

One hundred fifty four Siewert type II cases were enrolled: 124 men (80.5%), 30 women (19.5%), median age 65.5 (interquartile range 58-71); Intestinal type 91 (59%) and Diffuse type 63 (41%).

You may qualify if:

Siewert type II adenocarcinoma \> 18 year submitted to primary surgery

Sponsors & Collaborators

University of Bologna
Otherlead

Study Sites (2)

Department of Medical and Surgical Sciences University of Bologna

Bologna, Bo, 40138, Italy

Sandro Mattioli - Alma Mater Studiorum-University

Bologna, BO, 40138, Italy

Biospecimen

Retention: SAMPLES WITHOUT DNA

Surgical specimen

MeSH Terms

Conditions

Esophageal NeoplasmsAdenocarcinoma Of Esophagus

Condition Hierarchy (Ancestors)

Gastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsHead and Neck NeoplasmsDigestive System DiseasesEsophageal DiseasesGastrointestinal Diseases

Study Officials

Sandro Mattioli - Alma M Studiorum-University, MD
Department of Medical and Surgical Sciences
PRINCIPAL INVESTIGATOR

Enrollment

154 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: RETROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Associate Professor

Study Record Dates

First Submitted

January 23, 2018

First Posted

January 30, 2018

Study Start

January 1, 2007

Actual (reported)

Siewert Type II Esophageal Adenocarcinoma: Relationship Between Histology and Survival

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (2)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (2)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations