Social Behavior in Depression
HLGDep
1 other identifier
observational
25
1 country
1
Brief Summary
In the project, investigators basically plan to test the difference in social behavior and social cognition between depressive patients and healthy individuals. To test this, investigators plan to use traditional or novel behavioral experiment paradigms to target various behaviors.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Feb 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2017
CompletedFirst Submitted
Initial submission to the registry
January 22, 2018
CompletedFirst Posted
Study publicly available on registry
January 30, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 16, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2018
CompletedFebruary 6, 2018
February 1, 2018
1 year
January 22, 2018
February 4, 2018
Conditions
Outcome Measures
Primary Outcomes (6)
Prosocial behavior
The prosocial behavior will be assessed by conventional economic games, including dictator game, message game, and ultimatum game.
Baseline
Cognitive flexibility
Cognitive flexibility will be assessed by psychological cognitive paradigm, i.e. reversal learning paradigm. The participants will be asked to choose the item with high probability to win reward.
Baseline
Valuation of social information
The valuation of social information was measured by psychological paradigm, developed from animal studies, called "pay-per-view". The participants will be asked make decision about more social information or more monetary reward.
Baseline
Optimism bias
Participants will complete two sessions of life event estimation, i.e. estimating their likelihood of experiencing each event on a self-paced basis.
Baseline
Emotion recognition
After viewing a video, participants will be asked to judge the person's attitude in the video. Through this paradigm, investigators could test emotional bias in social interaction in depressive patients.
Baseline
Model-free & model-based tendency
Participants will be asked to complete a two-stage task, by choosing the stimuli with high probability to obtain reward.
Baseline
Eligibility Criteria
Individuals diagnosed with depression and healthy control
You may qualify if:
- Age range between 18 and 60
- Education experience above high school
- Score for Hamilton's Depression Scale \>=17
- Diagnosis of depression through Scid
You may not qualify if:
- Undergoing electric shock treatment in 3 months
- Excluding those who with bipolar disorder
- Excluding those who with postpartum depression
- Excluding those who with hysteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Beijing Normal Universitylead
- Huilongguan Hospitalcollaborator
Study Sites (1)
Huilongguan Hospital
Beijing, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Yina Ma, Doctor
Beijing Normal University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Target Duration
- 1 Month
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
January 22, 2018
First Posted
January 30, 2018
Study Start
February 1, 2017
Primary Completion
February 16, 2018
Study Completion
March 1, 2018
Last Updated
February 6, 2018
Record last verified: 2018-02