NCT03413670

Brief Summary

In the project, investigators plan to test difference of social cognition between depressive patients and healthy individuals and the brain activation underlying the difference to further understand the neural mechanism of depressive disorder.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
25

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2017

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2017

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

January 22, 2018

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 29, 2018

Completed
10 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 8, 2018

Completed
21 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2018

Completed
Last Updated

February 7, 2018

Status Verified

February 1, 2018

Enrollment Period

1.1 years

First QC Date

January 22, 2018

Last Update Submit

February 5, 2018

Conditions

Depression

Outcome Measures

Primary Outcomes (6)

  • emotion recognition

    After viewing a video, participants will be asked to judge the person's attitude in the video. Through this paradigm, investigators could test emotional bias in social interaction in depressive patients.

    Baseline

  • resting state

    In this part, investigators basically want to test the automatic neural activity for depressive patients while they are resting.

    Baseline

  • self-reflection

    Participants will be asked to judge the discrepancy between actual self and ideal self.

    Baseline

  • response to negative stimuli

    investigators used face-matching task to measure their response to negative stimuli. The participants will be asked to detect the identical face with same emotion.

    Baseline

  • structure

    Investigators scanned structural images to detect the difference between clinical population and healthy population.

    Baseline

  • white matter

    Investigators scanned DTI to detect the difference between clinical population and healthy population.

    Baseline

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Individuals diagnosed with depression and healthy control

You may qualify if:

  • Age range between 18 and 60
  • Education experience above high school
  • Score for Hamilton's Depression Scale \>=17
  • Diagnosis of depression through Scid

You may not qualify if:

  • Undergoing electric shock treatment in 3 months
  • Excluding those who with bipolar disorder
  • Excluding those who with postpartum depression
  • Excluding those who with hysteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Huilongguan Hospital

Beijing, China

RECRUITING

MeSH Terms

Conditions

Depression

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Central Study Contacts

Yina Ma, Doctor

CONTACT

+8613810258647yma@bnu.edu.cn

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Target Duration
1 Month
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 22, 2018

First Posted

January 29, 2018

Study Start

January 1, 2017

Primary Completion

February 8, 2018

Study Completion

March 1, 2018

Last Updated

February 7, 2018

Record last verified: 2018-02

Locations

CN(1)