NCT03412656

Brief Summary

The trial is designed to test the effectiveness of a force-feedback cuff in combination with a myoelectric prosthesis in conveying information on grasp strength to the user, as well as the user's preference regarding the feature.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
27

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 17, 2017

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

January 21, 2018

Completed
5 days until next milestone

First Posted

Study publicly available on registry

January 26, 2018

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 14, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 14, 2019

Completed
Last Updated

November 20, 2020

Status Verified

November 1, 2020

Enrollment Period

1.7 years

First QC Date

January 21, 2018

Last Update Submit

November 18, 2020

Conditions

Keywords

CUFFSoft Hand ProSHPSH ProSoftHand

Outcome Measures

Primary Outcomes (2)

  • Conveyance of force feedback

    Assessments will measure the extent to which the CUFF device conveys haptic force feedback, when used in combination with the Soft Hand Pro.

    1 year

  • Improvement to device embodiment through addition of grip force feedback

    Assessments will determine any improvement of device embodiment from the addition of grip force feedback to the Soft Hand Pro.

    1 year

Study Arms (2)

Patient

EXPERIMENTAL

Testing will include assessments of activities of daily living (ADLs) by a physical therapist, biomechanical measures of forces applied to objects and motion of the upper limb collected during commonly-performed tasks, and surveys assessing user preference regarding the force feedback feature, all while using the SoftHand Pro myoelectric lower arm prosthetic and the CUFF force feedback devices in tandem, utilizing the subjects' own prosthetic sockets. Grip force will be recorded using sensors attached to the CUFF device. During each session, videos will be obtained of the subjects performing tasks for kinematics analysis. The experimental sessions are organized into one to two sessions, comprising up to 16 hours, as determined by subject availability.

Device: SoftHand Pro with CUFF force feedback device

Control

OTHER

Testing will include assessments of activities of daily living (ADLs) by a physical therapist, biomechanical measures of forces applied to objects and motion of the upper limb collected during commonly-performed tasks, and surveys assessing user preference regarding the force feedback feature, all while using the SoftHand Pro myoelectric lower arm prosthetic and the CUFF force feedback devices in tandem, utilizing an adapter simulating a prosthetic socket. Grip force will be recorded using sensors attached to the CUFF device. During each session, videos will be obtained of the subjects performing tasks for kinematics analysis. The experimental sessions are organized into one to two sessions, comprising up to 16 hours, as determined by subject availability.

Device: SoftHand Pro with CUFF force feedback device

Interventions

Participants will complete various movement and activity of daily living (ADL) assessments to test the effectiveness of the CUFF device in combination with the Soft Hand Pro (SHP) in conveying haptic force feedback to patients with transradial limb loss, and to assess the extent to which the grip force feedback improves the embodiment of the prosthetic device.

Also known as: SoftHand, SoftHand Pro, CUFF, SHpro
ControlPatient

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age \> 18 years.
  • no prior experience with the CUFF device.
  • history of elbow disarticulation, transradial, or transhumeral limb loss (non-control subjects only).

You may not qualify if:

  • amputation for less than 6 months
  • clinical history of brachial plexopathy, cervical radiculopathy or polyneuropathy
  • orthopedic, joint degeneration (i.e., arthritis, verified by x-ray) affecting the hand or cervical spine that severely limit upper limb function
  • visual problems that would interfere with the grasp task
  • co-existing central nervous system disease with symptoms that limit upper extremity function (e.g., multiple sclerosis, motor neuron disease, myasthenia gravis, Parkinson's disease, dystonia) revealed in medical history
  • significant rigidity as assessed through range of motion testing
  • active psychiatric illness
  • significant cognitive impairments (a score \< 24 on the Mini-Mental State Examination)
  • use of medications that might affect sensory and/or motor functions
  • inability to effectively control myoelectrics for study purposes (control subjects only)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Location

Related Links

MeSH Terms

Conditions

Amputation, Traumatic

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

  • Kristin D. Zhao, Ph.D.

    Mayo Clinic

    PRINCIPAL INVESTIGATOR
  • Karen L. Andrews, M.D.

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DEVICE FEASIBILITY
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 21, 2018

First Posted

January 26, 2018

Study Start

October 17, 2017

Primary Completion

June 14, 2019

Study Completion

June 14, 2019

Last Updated

November 20, 2020

Record last verified: 2020-11

Data Sharing

IPD Sharing
Will not share

Locations