NCT03406234

Brief Summary

An observational study was conducted in a health examination center to distinguish risk factors for health in a randomly recruited volunteers of Chinese population.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,650

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2013

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2013

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2013

Completed
4 years until next milestone

First Submitted

Initial submission to the registry

January 8, 2018

Completed
15 days until next milestone

First Posted

Study publicly available on registry

January 23, 2018

Completed
Last Updated

January 23, 2018

Status Verified

January 1, 2018

Enrollment Period

12 months

First QC Date

January 8, 2018

Last Update Submit

January 12, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Circulating 25OHD concentration.

    Jan., 2014 - May., 2015

Secondary Outcomes (5)

  • Body mass index

    Jan.-Dec., 2013

  • Plasma glucose

    Jan.-Dec., 2013

  • DNA polymorphisms

    Jan., 2014 - Dec., 2017

  • Plasma lipids

    Jan.-Dec., 2013

  • Blood pressure

    Jan.-Dec., 2013

Study Arms (1)

A group of participants

Other: No intervention.

Interventions

Cross-sectional observation without interventions.

A group of participants

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Both males and females were included.

You may qualify if:

  • Han population, living in Shenzhen City for \> 2 y, not in pregnancy, without hepatic diseases and renal diseases

You may not qualify if:

  • caught by organic diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shenzhen Center for Chronic Disease Control

Shenzhen, Guangdong, 518020, China

Location

Related Publications (4)

  • Chen J, Yun C, He Y, Piao J, Yang L, Yang X. Vitamin D status among the elderly Chinese population: a cross-sectional analysis of the 2010-2013 China national nutrition and health survey (CNNHS). Nutr J. 2017 Jan 14;16(1):3. doi: 10.1186/s12937-016-0224-3.

  • Santos BR, Mascarenhas LP, Boguszewski MC, Spritzer PM. Variations in the vitamin D-binding protein (DBP) gene are related to lower 25-hydroxyvitamin D levels in healthy girls: a cross-sectional study. Horm Res Paediatr. 2013;79:162-8. doi: 10.1159/000348847. Epub 2013 Mar 20.

  • Gozdzik A, Zhu J, Wong BY, Fu L, Cole DE, Parra EJ. Association of vitamin D binding protein (VDBP) polymorphisms and serum 25(OH)D concentrations in a sample of young Canadian adults of different ancestry. J Steroid Biochem Mol Biol. 2011 Nov;127(3-5):405-12. doi: 10.1016/j.jsbmb.2011.05.009. Epub 2011 Jun 12.

  • Zhou JC, Zhu Y, Gong C, Liang X, Zhou X, Xu Y, Lyu D, Mo J, Xu J, Song J, Che X, Sun S, Huang C, Liu XL. The GC2 haplotype of the vitamin D binding protein is a risk factor for a low plasma 25-hydroxyvitamin D concentration in a Han Chinese population. Nutr Metab (Lond). 2019 Jan 14;16:5. doi: 10.1186/s12986-019-0332-0. eCollection 2019.

Biospecimen

Retention: SAMPLES WITH DNA

Blood.

MeSH Terms

Conditions

Metabolic DiseasesNutrition DisordersGenetic Predisposition to Disease

Condition Hierarchy (Ancestors)

Nutritional and Metabolic DiseasesDisease SusceptibilityDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director of Molecular Biology Laboratory

Study Record Dates

First Submitted

January 8, 2018

First Posted

January 23, 2018

Study Start

January 1, 2013

Primary Completion

December 31, 2013

Study Completion

December 31, 2013

Last Updated

January 23, 2018

Record last verified: 2018-01

Data Sharing

IPD Sharing
Will not share

Locations