NCT03405610

Brief Summary

The aims of this study are to test a manualized mind body skills-building program aimed at preventing the development of chronic pain and disability following acute musculoskeletal injury in at-risk patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
55

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2015

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

December 3, 2017

Completed
2 months until next milestone

First Posted

Study publicly available on registry

January 23, 2018

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2018

Completed
Last Updated

August 17, 2018

Status Verified

August 1, 2018

Enrollment Period

3.1 years

First QC Date

December 3, 2017

Last Update Submit

August 16, 2018

Conditions

Keywords

PsychiatryPsychologyPsychosocialMind-Body

Outcome Measures

Primary Outcomes (7)

  • Feasibility of recruitment

    We will report number of patients approached, number who agreed to participate/were screened, number of patients randomized

    0 Weeks

  • Satisfaction with ToR

    3 questions assessing satisfaction with the physical recovery, with the care delivered, and with the clinician.

    4 weeks; 3 months

  • Acceptability

    We will report number of patients who finished ToR and UC and completed post-test from those who started the study (were randomized); We will also report number of participants who provided 3 months follow up

    4 weeks; 3 months

  • Feasibility of outcome measures

    We will report number of missing items and calculate reliability of outcome measures

    0 weeks; 4 weeks; 3 months

  • Adherence to ToR

    We will report number of participants who completed at least 3 out of 4 ToR sessions

    4 weeks.

  • Adherence to homework

    determined by number of homework logs returned

    4 weeks

  • Therapist adherence survey

    Items assessing whether the therapist taught each of the skills included in each of the 4 sessions

    4 weeks

Secondary Outcomes (6)

  • Pain Catastrophizing

    0 Weeks, 4 Weeks, 3 Months

  • Pain Anxiety

    0 Weeks, 4 Weeks, 3 Months

  • Depression

    0 Weeks, 4 Weeks, 3 Months

  • Post Traumatic Stress Disorder

    0 Weeks, 4 Weeks, 3 Months

  • Pain intensity

    0 Weeks, 4 Weeks, 3 Months

  • +1 more secondary outcomes

Study Arms (2)

Toolkit for Optimal Recovery after Injury

EXPERIMENTAL

The Toolkit for Optimal Recovery after Injury (ToR) is a mind body skills based program delivered individually via secure live video. The format is a 4-week program with weekly meetings and a focus on teaching skills to optimize recovery and prevent chronic pain and disability.

Behavioral: The Toolkit for Optimal Recovery after Injury

Usual Care

NO INTERVENTION

The Usual Care (UC) group will continue with their current medical care.

Interventions

The Toolkit for Optimal Recovery after Injury (ToR) is a skills based mind body program that was designed to prevent the development of chronic pain and disability following an acute musculoskeletal injury (e.g., fracture). The program has 4 sessions and it is delivered via live video. Patients learn myth about recovery after injury, false and real pain alarms, the fear avoidance model and how to prevent the disability spiral, mindfulness based exercises and activity pacing.

Also known as: ToR
Toolkit for Optimal Recovery after Injury

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of musculoskeletal injury in the past 1-2 months
  • years of age or older
  • English fluency and literacy
  • PCS OR, PASS score above median split

You may not qualify if:

  • Major medical comorbidity expected to worsen in the next 6 months
  • Comorbid chronic pain condition
  • Antidepressant medication change in the past 6 months
  • Secondary gains such as litigations or workers compensation procedures
  • Diagnosis of psychosis, bipolar disorder or active substance dependence (by self report)
  • Unwilling or unable to use videoconferencing

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

Location

Related Publications (1)

  • Vranceanu AM, Jacobs C, Lin A, Greenberg J, Funes CJ, Harris MB, Heng MM, Macklin EA, Ring D. Results of a feasibility randomized controlled trial (RCT) of the Toolkit for Optimal Recovery (TOR): a live video program to prevent chronic pain in at-risk adults with orthopedic injuries. Pilot Feasibility Stud. 2019 Feb 20;5:30. doi: 10.1186/s40814-019-0416-7. eCollection 2019.

MeSH Terms

Conditions

Fractures, Bone

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

  • Ana-Maria Vranceanu, PhD

    Massachusetts General Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Psychologist

Study Record Dates

First Submitted

December 3, 2017

First Posted

January 23, 2018

Study Start

July 1, 2015

Primary Completion

August 1, 2018

Study Completion

August 1, 2018

Last Updated

August 17, 2018

Record last verified: 2018-08

Locations