Breakfast and Metabolism in Men

NCT03399812 | Completed

• 1 other identifier: 1708038914
• Study Type: interventional
• Target: 33
• Locations: 1 country
• Sites: 1

Brief Summary

This study will determine the short-term postprandial effects of protein source at breakfast on energy metabolism, markers of metabolic health, appetite, and food intake and young and older men.

Conditions

Aging

Outcome Measures

Primary Outcomes (2)

• Energy expenditure

  Energy expended per minute will be measured using indirect calorimetry.

  Time frame is every 30 minutes for four hours following intervention.

• Appetite

  Appetite will be assessed using a traditional 100-mm visual analog scale (VAS) (3) with opposing anchors (e.g., "extremely hungry" or "not hungry at all") at time points 15, 30, 60, 90, 120, 180 and 240 min. Questions consisted of: "how hungry do you feel at this moment", "how full do you feel at this moment", "how strong is your desire to eat this moment" and "how much food do you think you can eat at this moment." Participants were asked to place an "X" on the 100-mm VAS in the place that pertained to their perceived appetite feelings at each time point." Participants were asked to place an "X" on the 100-mm VAS in the place that pertained to their perceived appetite feelings at each time point. The averages for each time point are taken to represent the feeling of appetitive at a particular time point.

  Time frame is every 30 minutes for four hours following intervention.

Secondary Outcomes (1)

• 24-hour food intake

  Food intake will be recorded for one day.

Other Outcomes (1)

• Appetite biomarkers

  Time frame is every 30 minutes for four hours following intervention.

Study Arms (2)

Whey protein isolate

EXPERIMENTAL

Dietary Supplement: Animal protein

Pea protein isolate

ACTIVE COMPARATOR

Dietary Supplement: Plant protein

Interventions

Animal protein DIETARY_SUPPLEMENT

The animal protein intervention is a smoothie containing 40 grams of whey protein isolate.

Whey protein isolate

Plant protein DIETARY_SUPPLEMENT

The animal protein intervention is a smoothie containing 40 grams of pea protein isolate.

Pea protein isolate

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male
• No medication
• Athlete (elite or professional)

You may not qualify if:

• Diet-related conditions
• Food allergies
• Does not regularly consume protein supplements
• Claustrophobic
• Underweight

Sponsors & Collaborators

• University of Arkansas, Fayetteville: lead

Study Sites (1)

University of Arkansas

Fayetteville, Arkansas, 72704, United States

Location

Related Publications (1)

• Hawley AL, Gbur E, Tacinelli AM, Walker S, Murphy A, Burgess R, Baum JI. The Short-Term Effect of Whey Compared with Pea Protein on Appetite, Food Intake, and Energy Expenditure in Young and Older Men. Curr Dev Nutr. 2020 Jan 22;4(2):nzaa009. doi: 10.1093/cdn/nzaa009. eCollection 2020 Feb.

  PMID: 32072131 DERIVED

MeSH Terms

Interventions

Plant Proteins

Intervention Hierarchy (Ancestors)

Proteins; Amino Acids, Peptides, and Proteins

Study Officials

• Jamie Baum

  University of Arkansas, Fayetteville

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: January 8, 2018
• First Posted: January 16, 2018
• Study Start: December 15, 2017
• Primary Completion: April 30, 2018
• Study Completion: June 30, 2018
• Last Updated: July 17, 2018

Record last verified: 2018-07

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)