NCT03378115

Brief Summary

The purpose of this study is to determine the magnitude of changes in energy expenditure and respiratory quotient (RQ) during sitting and standing in Asian men.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started May 2017

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 25, 2017

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

December 15, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

December 19, 2017

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 26, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 26, 2018

Completed
Last Updated

April 3, 2018

Status Verified

April 1, 2018

Enrollment Period

10 months

First QC Date

December 15, 2017

Last Update Submit

April 1, 2018

Conditions

Energy Expenditure

Outcome Measures

Primary Outcomes (1)

  • Measurement of energy expenditure and respiratory quotient (RQ) in sitting and standing positions

    Measured using Whole Body Calorimeter

    Up to 3 hours

Eligibility Criteria

Age21 Years - 40 Years
Sexmale(Gender-based eligibility)
Gender Eligibility DetailsHealthy males volunteers only
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Healthy Chinese/Malay/Indian

You may qualify if:

  • Healthy Male
  • Age between 21-40 years old
  • Chinese, Malay or Indian Ethnicity
  • Body mass index between 18.5 - 28 kg/m2
  • Normal blood pressure (\<140/90 mmHg)
  • Do not have metabolic diseases (such as diabetes, hypertension etc.)
  • Do not have glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • Do not take prescription medication that may affect metabolism
  • Do not intentionally restrict food intake
  • Do not have intolerances or allergies to test foods

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clinical Nutrition Research Cenre

Singapore, 117599, Singapore

Location

Related Publications (1)

  • Camps SG, Koh HR, Henry CJ. Posture economy: the importance of metabolic state on metabolic phenotype assessment and the energy cost of sitting and standing. A whole body calorimetry trial. Eur J Clin Nutr. 2022 Aug;76(8):1178-1185. doi: 10.1038/s41430-022-01077-7. Epub 2022 Feb 1.

    PMID: 35105942DERIVED

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
OTHER
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

December 15, 2017

First Posted

December 19, 2017

Study Start

May 25, 2017

Primary Completion

March 26, 2018

Study Completion

March 26, 2018

Last Updated

April 3, 2018

Record last verified: 2018-04

Locations

SG(1)