Influence of an Endometrioma on Oocyte Quality
ENDOVOC
1 other identifier
observational
80
0 countries
N/A
Brief Summary
The purpose of this study is to evaluate if there are differences in oocyte quality depending on whether these oocytes come from an ovary in contact with an endometrioma.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2017
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2017
CompletedFirst Submitted
Initial submission to the registry
January 17, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2017
CompletedFirst Posted
Study publicly available on registry
November 24, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2018
CompletedNovember 24, 2017
January 1, 2017
10 months
January 17, 2017
November 20, 2017
Conditions
Outcome Measures
Primary Outcomes (2)
Percentage of mature oocytes
Number of MII oocytes from the total of cumulus granulosa cell-oocyte complex by 100
Up to 36 months
Fertilization rate
Number of oocytes with pronuclear activation after ICSI procedure from the total oocytes microinjected by 100
Up to 36 months
Study Arms (2)
Endometriosis
No drugs are administered. It is an observational study. Collect retrospectively data
No endometriosis
No drugs are administered. It is an observational study. Collect retrospectively data
Interventions
Eligibility Criteria
Patients \<40 years, BMI \<30kg / m2,
You may qualify if:
- Patients \<40 years, BMI \<30kg / m2,
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- IVI Vigolead
Related Publications (3)
Garcia-Velasco JA, Mahutte NG, Corona J, Zuniga V, Giles J, Arici A, Pellicer A. Removal of endometriomas before in vitro fertilization does not improve fertility outcomes: a matched, case-control study. Fertil Steril. 2004 May;81(5):1194-7. doi: 10.1016/j.fertnstert.2003.04.006.
PMID: 15136074BACKGROUNDGarrido N, Navarro J, Remohi J, Simon C, Pellicer A. Follicular hormonal environment and embryo quality in women with endometriosis. Hum Reprod Update. 2000 Jan-Feb;6(1):67-74. doi: 10.1093/humupd/6.1.67.
PMID: 10711831BACKGROUNDFilippi F, Benaglia L, Paffoni A, Restelli L, Vercellini P, Somigliana E, Fedele L. Ovarian endometriomas and oocyte quality: insights from in vitro fertilization cycles. Fertil Steril. 2014 Apr;101(4):988-93.e1. doi: 10.1016/j.fertnstert.2014.01.008. Epub 2014 Mar 3.
PMID: 24602751BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Elkin Muñoz, Principal Investigator
IVI Vigo
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 17, 2017
First Posted
November 24, 2017
Study Start
January 1, 2017
Primary Completion
November 1, 2017
Study Completion
January 1, 2018
Last Updated
November 24, 2017
Record last verified: 2017-01
Data Sharing
- IPD Sharing
- Will not share