NCT02308995

Brief Summary

The aim of this randomized controlled trial is to compare operative data and early postoperative outcomes of laparoscopic excision of endometrioma using barbed sutures with those of laparoscopic excision of endometrioma using conventional sutures.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for phase_2

Timeline
Completed

Started Dec 2014

Shorter than P25 for phase_2

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2014

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

December 3, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 5, 2014

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2016

Completed
Last Updated

January 29, 2016

Status Verified

January 1, 2016

Enrollment Period

1.2 years

First QC Date

December 3, 2014

Last Update Submit

January 28, 2016

Conditions

Keywords

EndometriosisLaparoscopyBarbed sutures

Outcome Measures

Primary Outcomes (1)

  • Suturing time of endometrioma bed

    During cystectomy operation

Secondary Outcomes (1)

  • Operative time

    During cystectomy operation

Study Arms (2)

Cystectomy using barbed sutures

EXPERIMENTAL

Endometrioma bed is sutured with barbed sutures

Procedure: Cystectomy using barbed suturesDevice: V-Loc (Covidien, Mansfield, MA)

Cystectomy using conventional sutures

ACTIVE COMPARATOR

Endometrioma bed is sutured with conventional sutures

Procedure: Cystectomy using conventional suturesDevice: polyglactin 910 suture(VICRYL™, Ethicon Inc, Sommerville, NJ)

Interventions

A sharp transverse cortical incision was made over the endometroma using unipolar hook and a cleavage plane was developed by sharp dissection. After the identification of the cleavage plane, the entire cyst will be enucleated by means of adequate traction with a strong grasper and counter-traction maneuvers with another grasping forceps . The ovarian edges will be re-approximated by using V-Loc (Covidien, Mansfield, MA).

Cystectomy using barbed sutures

A sharp transverse cortical incision was made over the endometroma using unipolar hook and a cleavage plane was developed by sharp dissection. After the identification of the cleavage plane, the entire cyst will be enucleated by means of adequate traction with a strong grasper and counter-traction maneuvers with another grasping forceps . The ovarian edges will be re-approximated by using polyglactin 910 suture(VICRYL™.; Ethicon Inc, Sommerville, NJ) .

Cystectomy using conventional sutures
Cystectomy using barbed sutures
Cystectomy using conventional sutures

Eligibility Criteria

Age18 Years - 55 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Unilateral endometrioma more than 3 cm in mean diameter

You may not qualify if:

  • Bilateral endometriomata
  • Conversion of laparoscopy to laparotomy
  • Contraindications for general anesthesia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Aljazeera hospital

Giza, Giza Governorate, Egypt

RECRUITING

MeSH Terms

Conditions

Endometriosis

Condition Hierarchy (Ancestors)

Genital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital Diseases

Study Officials

  • Usama M Fouda, M.D,PhD

    Aljazeera Hospital

    STUDY CHAIR

Central Study Contacts

Usama M Fouda, M.D,PhD

CONTACT

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
M.D, PhD

Study Record Dates

First Submitted

December 3, 2014

First Posted

December 5, 2014

Study Start

December 1, 2014

Primary Completion

March 1, 2016

Study Completion

March 1, 2016

Last Updated

January 29, 2016

Record last verified: 2016-01

Locations