NCT03331705

Brief Summary

This is a prospective, multicenter, single-arm, open-label clinical usability study in subjects who are candidates for office diagnostic cystoscopy. The primary objective of this initial device assessment is to evaluate the performance of a new cystoscope for direct visualization of the urethra and bladder.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Nov 2016

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 5, 2016

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

October 26, 2017

Completed
11 days until next milestone

First Posted

Study publicly available on registry

November 6, 2017

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 5, 2018

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 5, 2018

Completed
Last Updated

November 6, 2017

Status Verified

October 1, 2017

Enrollment Period

1.7 years

First QC Date

October 26, 2017

Last Update Submit

November 2, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Assessment of the utility and performance of the cystoscope by the physician

    Ranking with Likert Scale on ease of advancement, visibility of tissue and structures, and removal of the device

    during the procedure

Secondary Outcomes (1)

  • Patient tolerance of the procedure

    during and within 5 days after the procedure

Study Arms (1)

Use of new cystoscope

Patients in which the cystoscope is used.

Device: Uro-C (Use of new cystoscope)

Interventions

Diagnostic cystoscopic procedure of the urethra and bladder

Use of new cystoscope

Eligibility Criteria

Age18 Years - 90 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Females requiring a diagnostic cystoscopic procedure

You may qualify if:

  • Otherwise healthy adult (18 years of age or older) women presenting for cystoscopy for diagnostic purposes; and
  • Ambulatory and able to undergo routine cystoscopy in the lithotomy position.

You may not qualify if:

  • History of prior bladder/urethral surgery other than TURBT; or
  • History of interstitial cystitis; or
  • Presence of urinary tract infection (UTI); or
  • Gross hematuria; or
  • History of pelvic radiation therapy; or
  • Procidentia; or
  • Unable to read, understand, and/or provide a ranking of pain level during the procedure; or
  • Unable or unwilling to provide consent to participation in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Las Vegas Urology

Las Vegas, Nevada, 89128, United States

RECRUITING

MeSH Terms

Conditions

Urinary Bladder Neoplasms

Condition Hierarchy (Ancestors)

Urologic NeoplasmsUrogenital NeoplasmsNeoplasms by SiteNeoplasmsFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesUrinary Bladder DiseasesUrologic DiseasesMale Urogenital Diseases

Study Officials

  • Bela Denes, MD

    UroSee Corporation

    STUDY DIRECTOR

Central Study Contacts

Thomas Lawson, PhD

CONTACT

Bela Denes, MD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 26, 2017

First Posted

November 6, 2017

Study Start

November 5, 2016

Primary Completion

July 5, 2018

Study Completion

September 5, 2018

Last Updated

November 6, 2017

Record last verified: 2017-10

Locations