NCT03300856

Brief Summary

Background: TMS stands for transcranial magnetic stimulation. It is a non-invasive way to stimulate the brain. It helps researchers study the nervous system. TMS can assess central motor conduction time (CMCT). That can be used to diagnose some diseases. It can also show how well treatments are working. Researchers want to study the records of people who have already had TMS. They want to see how it relates to the results of diagnostic studies. Objectives: To study the results of transcranial magnetic stimulation in certain neurological disorders. To create a descriptive analysis of the results. Eligibility: Records that are already in the NINDS database Design: The study will not enroll any participants. Researchers will search the database for certain terms. These include TMS, CMTC, and motor evoked potentials. This will identify records of people who had TMS for diagnosis. Using data from the records, researchers will calculate CMCT. They will note other data that relate to CMCT. Researchers will analyze their findings. They will write a review article. Personal data will be removed from all the records before the findings are analyzed.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
225

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2017

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 3, 2017

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 4, 2017

Completed
Same day until next milestone

Study Start

First participant enrolled

October 4, 2017

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 19, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 19, 2018

Completed
Last Updated

August 1, 2018

Status Verified

July 1, 2018

Enrollment Period

10 months

First QC Date

October 3, 2017

Last Update Submit

July 31, 2018

Conditions

Keywords

Transcranial Magnetic Stimulation (TMS)Electrophysiology

Outcome Measures

Primary Outcomes (1)

  • Summary of central motor conduction studies in neurological disorders

    Study completion

Study Arms (1)

Chart Review

Existing records of patients within the NINDS database who have had TMS performed to measure central motor conduction time (CMCT).

Eligibility Criteria

Age18 Years - 130 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Existing records of patients within the NINDS database who have had TMS performed to measure central motor conduction time (CMCT).

You may qualify if:

  • Patients who were seen in the NINDS EMG section for diagnostic TMS studies
  • Patients tested between 1998 and 2017
  • Greater than or equal to age 18.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Institute of Neurological Disorders and Stroke (NINDS)

Bethesda, Maryland, 20892, United States

Location

MeSH Terms

Conditions

Nervous System Diseases

Study Officials

  • Mary Kay Floeter, M.D.

    National Institute of Neurological Disorders and Stroke (NINDS)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
NIH
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 3, 2017

First Posted

October 4, 2017

Study Start

October 4, 2017

Primary Completion

July 19, 2018

Study Completion

July 19, 2018

Last Updated

August 1, 2018

Record last verified: 2018-07

Locations