NCT03288194

Brief Summary

This research study has been designed to test the efficacy of telephone-delivered Problem-Solving Treatment (PST) for improving the quality of life (QoL) in outpatients with stable heart failure (HF).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
14

participants targeted

Target at below P25 for not_applicable heart-failure

Timeline
Completed

Started Oct 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2015

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 24, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 24, 2017

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

September 15, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 19, 2017

Completed
Last Updated

May 6, 2022

Status Verified

May 1, 2022

Enrollment Period

1.6 years

First QC Date

September 15, 2017

Last Update Submit

May 2, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in Kansas City Cardiomyopathy Questionnaire

    The Kansas City Cardiomyopathy Questionnaire is a 23-item, self-administered instrument that quantifies physical function, symptoms (frequency, severity and recent change), social function, self-efficacy and knowledge, and quality of life.

    1 month, 2 months, 3 months, 4 months, 5 months

Secondary Outcomes (1)

  • Change in Beck Depression Inventory

    1 month, 2 months, 3 months, 4 months, 5 months

Study Arms (2)

Problem-Solving Treatment

EXPERIMENTAL

Problem-Solving Treatment is a structured, yet flexible, form of cognitive-behavioral psychotherapy intended to increase problem-solving skills.

Behavioral: Problem-Solving Treatment

Time Management

ACTIVE COMPARATOR

Time Management is a structured, yet flexible, intervention intended to increase creativity.

Behavioral: Time Management

Interventions

Problem-Solving Treatment
Time ManagementBEHAVIORAL
Time Management

Eligibility Criteria

Age21 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Outpatient
  • Age \> 21
  • Exhibits symptoms of hear failure (NYHA Class II or III)
  • Left ventricular ejection fraction (LVEF) \>= 40%
  • Kansas City Cardiomyopathy Questionnaire (KCCQ) summary score \< 60

You may not qualify if:

  • Cannot speak English
  • Lack telephone access
  • Unwilling to be randomized, or
  • Unavailable for the study period
  • Awaiting a heart transplant (United Network for Organ Sharing Status 1A or 1B), or
  • Planned (within 6 months) cardiac surgery
  • Cognitive impairment indicative of dementia
  • Recent (3 months)
  • acute myocardial infarction,
  • cardiac decompensation, or
  • HF-related hospitalization.
  • Use intravenous inotropic medication
  • Use an assistive circulatory device
  • Significantly reduced life expectancy due to co-morbidity (e.g., malignancy)
  • Currently receiving mental health counseling;
  • +5 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Colorado

Denver, Colorado, 80045, United States

Location

MeSH Terms

Conditions

Heart Failure

Interventions

Time Management

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Psychology, IndustrialPsychologyBehavioral SciencesBehavioral Disciplines and ActivitiesOrganization and AdministrationHealth Services Administration

Study Officials

  • Jonathan A Shaffer, PhD

    University of Colorado, Denver

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 15, 2017

First Posted

September 19, 2017

Study Start

October 1, 2015

Primary Completion

April 24, 2017

Study Completion

April 24, 2017

Last Updated

May 6, 2022

Record last verified: 2022-05

Locations