Expression of TET1 Gene in Acute Leukaemia
1 other identifier
observational
100
0 countries
N/A
Brief Summary
The aim of the present study is to detect the expression of TET 1 gene in patients with acute leukemia and its correlation with clinical and pathological criteria of the patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Nov 2017
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 29, 2017
CompletedFirst Posted
Study publicly available on registry
August 30, 2017
CompletedStudy Start
First participant enrolled
November 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2018
CompletedAugust 30, 2017
August 1, 2017
1 year
August 29, 2017
August 29, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
expression of TET1 gene in acute leukemia
role of TET1 gene expression in leukemogenesis
baseline
Interventions
Real Time PCR is based on the detection of the fluorescence produced by a reporter molecule which increases, as the reaction proceeds. These fluorescent reporter molecules include dyes that bind to the double-stranded DNA or sequence specific probes . Moreover, there is no need for the post PCR processing which saves the resources and the time. .
Eligibility Criteria
acute leukemia patients at diagnosis or relapse .
You may qualify if:
- \- sample from acute leukemia patients at diagnosis or relapse . healthy subjects as control .
You may not qualify if:
- Patients having any other haematological malignancies.
- Patient with acute leukemia in remission
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (2)
Jain A, Varma S, Garg R, Malhotra P. Unilateral Gynaecomastia in a Young Man with Chronic Myeloid Leukemia. Indian J Hematol Blood Transfus. 2017 Sep;33(3):448-450. doi: 10.1007/s12288-016-0762-z. Epub 2016 Dec 19.
PMID: 28824259BACKGROUNDLee BS, Jan YD, Huang GS, Huang CH, Chou HY, Wang JS, Tseng WY. Effect of dentin bonding agent diffusing through dentin slices on the reactive oxygen species production and apoptosis of pulpal cells. J Formos Med Assoc. 2015 Apr;114(4):339-46. doi: 10.1016/j.jfma.2012.12.009. Epub 2013 Feb 13.
PMID: 25839767BACKGROUND
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Resident doctor of clinical pathology department South Egypt Cancer Institute
Study Record Dates
First Submitted
August 29, 2017
First Posted
August 30, 2017
Study Start
November 1, 2017
Primary Completion
November 1, 2018
Study Completion
December 1, 2018
Last Updated
August 30, 2017
Record last verified: 2017-08