Key Insights

Highlights

Success Rate

87% trial completion

Published Results

28 trials with published results (13%)

Research Maturity

77 completed trials (37% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

5.8%

12 terminated out of 208 trials

Success Rate

86.5%

-0.1% vs benchmark

Late-Stage Pipeline

5%

10 trials in Phase 3/4

Results Transparency

36%

28 of 77 completed with results

Key Signals

28 with results87% success12 terminated

Data Visualizations

Phase Distribution

154Total
Not Applicable (48)
Early P 1 (2)
P 1 (49)
P 2 (45)
P 3 (8)
P 4 (2)

Trial Status

Completed77
Recruiting48
Unknown35
Active Not Recruiting16
Not Yet Recruiting13
Terminated12

Trial Success Rate

86.5%

Benchmark: 86.6%

Based on 77 completed trials

Clinical Trials (208)

Showing 20 of 20 trials
NCT03595800Phase 3CompletedPrimary

Extension of a Study of Allogeneic Hematopoietic Stem Cell Transplantation From One Haplotype Mismatch Related Donor or From an Unrelated Donor to Younger Patients Eligible for Reduced-intensity Conditioning Regimen

NCT04811560Phase 1RecruitingPrimary

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

NCT03779854Phase 2Active Not Recruiting

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

NCT07831668Not Yet RecruitingPrimary

Real World Assessment of Venous Thromboembolic Risk in Hospitalized Patients With Acute Leukemia

NCT04224974Not ApplicableRecruitingPrimary

Emotion and Symptom-Focused Engagement Trial for Individuals With Acute Leukemia

NCT06421155Not ApplicableSuspendedPrimary

Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia

NCT07819396Phase 2Not Yet Recruiting

Depletion of CD45RA Positive Naive T Cells for the Prevention of Graft Versus Host Disease in Older Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Leukemia or Myelodysplastic Syndrome

NCT07710781Not ApplicableNot Yet Recruiting

Study to Characterize Mismatched to Fully HLA-Matched Ossium HPC, Marrow and Living Donor Transplantation in Patients With Hematologic Malignancies

NCT05589896Phase 1Active Not RecruitingPrimary

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

NCT07796620Phase 1Not Yet RecruitingPrimary

Sirolimus+Ruxolitinib+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to CNI

NCT06907797Not ApplicableRecruitingPrimary

Tools for Reducing Inequity in Acute Leukemia (TRIAL): Beta Testing

NCT07809984Not ApplicableNot Yet RecruitingPrimary

Prevention of Oral Mucositis in Adults in With Hematologic Malignancy

NCT05320809Phase 1CompletedPrimary

Study of 3D189 in Patients With Hematologic Malignancies

NCT07805746Not Yet Recruiting

Peri-graft Cytokine Profile: Influence of Hematologic Disease and Donor Type

NCT07573111Phase 1RecruitingPrimary

Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation

NCT06001788Phase 1Recruiting

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT07565220Phase 1Recruiting

Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

NCT06001385Phase 2Active Not Recruiting

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis

NCT04013685Phase 1Active Not Recruiting

Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

NCT05428176Not ApplicableActive Not RecruitingPrimary

A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer Survivors

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