Effects of Benzocaine 20% Topical Anesthetic and no Topical Agent on Pain Perception During Intra-oral Injections
Efficacy of Topical Benzocaine in Anterior Maxilla: A Randomised Controlled Trial
1 other identifier
interventional
100
1 country
1
Brief Summary
The aim of this randomized controlled trial. is to test the efficacy of topical anesthesia against the use of no topical agent during buccal infiltration in maxillary anterior teeth. The rationale behind this comparison is to evaluate the practical, clinical outcome of not using any topical agent if in fact topical anesthesia does not reduce pain as reported by various studies and if consequently its usage was to be discontinued.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Aug 2017
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 16, 2017
CompletedFirst Submitted
Initial submission to the registry
August 18, 2017
CompletedFirst Posted
Study publicly available on registry
August 24, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 16, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
September 20, 2017
CompletedOctober 9, 2017
October 1, 2017
1 month
August 18, 2017
October 6, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Pain score on needle penetration
Pain score measured by numeric pain rating scale
Immediately
Pain score on local anesthesia deposition
Pain score measured by numeric pain rating scale
Immediately
Study Arms (2)
Control group
NO INTERVENTIONTopical Anesthesia
Study group
EXPERIMENTALNo topical anesthesia
Interventions
Lack of use of topical anesthesia application prior to infiltration injection intra-orally
Eligibility Criteria
You may qualify if:
- Above the age of 18
- Males and females both
- Participants requiring extraction of maxillary anterior teeth
- Intact or minimally restored anterior teeth
- Patients with American Society of Anesthesiologists physical status of 1 or 2
You may not qualify if:
- Participants with physical American Society of Anesthesiologists physical status of 3 or 4
- Showing signs of inflammation in the area to be injected
- Having known allergy to any of the agents used in the study
- Used anti- anxiety drugs or sedatives in the past two weeks
- Have taken analgesics on the day of data collection
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Nurain Rehmanlead
Study Sites (1)
CMH Lahore Medical College and Institute of Dentistry
Lahore, Pakistan
Related Publications (1)
Rehman N, Qazi SR. Efficacy of Topical Benzocaine in Maxilla: A Randomized Controlled Trial. Anesth Prog. 2019 Spring;66(1):24-29. doi: 10.2344/anpr-66-01-01.
PMID: 30883233DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Nurain Rehman
CMH Lahore Medical College and Institute of Dentistry
- STUDY DIRECTOR
Samir Qazi, FFDRCSI
CMH Lahore Medical College and Institute of Dentistry
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Final Year Student BDS
Study Record Dates
First Submitted
August 18, 2017
First Posted
August 24, 2017
Study Start
August 16, 2017
Primary Completion
September 16, 2017
Study Completion
September 20, 2017
Last Updated
October 9, 2017
Record last verified: 2017-10
Data Sharing
- IPD Sharing
- Will not share