NCT03014336

Brief Summary

The drawbacks of chemical CO2 absorbers include the production of compounds harmful to patients that also lead into increased cost and environmental impact, as well as the daily disposal of compound special waste. Sustainable management of general anesthesia is a growing concern. Continually diluting anesthetic circuits, and the disposal of chemical granulate are serious environmental problems.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
286

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 12, 2016

Completed
3 months until next milestone

First Posted

Study publicly available on registry

January 9, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

March 20, 2017

Completed
5.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 10, 2022

Completed
2.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 24, 2024

Completed
1.6 years until next milestone

Results Posted

Study results publicly available

February 23, 2026

Completed
Last Updated

February 23, 2026

Status Verified

February 1, 2026

Enrollment Period

5.1 years

First QC Date

October 12, 2016

Results QC Date

March 18, 2025

Last Update Submit

February 4, 2026

Conditions

Keywords

co2 removal, anesthesia

Outcome Measures

Primary Outcomes (1)

  • End-tidal CO2 Concentration (%)

    The mean concentration of carbon dioxide during the expiratory cycle, measured as a percentage (%), measured over the course of the surgical procedure.

    From the start to the end of the intra-operative period for each participant

Other Outcomes (1)

  • Fraction of Anaesthetic Agent (%)

    From the start to the end of the intra-operative period for each participant

Study Arms (2)

Control

NO INTERVENTION

Patients receive standard care with a standard CO2 absorber and agree to include their data in the study.

memsorb

EXPERIMENTAL

Patients agree to receive standard care but using memsorb, the new CO2 filter evaluated in this study.

Device: memsorb

Interventions

memsorbDEVICE

memsorb is a CO2 filter replacing current chemical CO2 absorbers

memsorb

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • American Society of Anesthesiologists Physical Status Class I, II, III (low-medium risk patient)
  • English-speaking patients

You may not qualify if:

  • Self-reported as pregnant
  • American Society of Anesthesiologists Physical Status Class IV (high risk patient)
  • Patients scheduled for emergency surgery
  • Documented respiratory disease, including COPD and severe asthma
  • Documented elevated pressure in the brain (intra cranial pressure, ICP)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Queen Elizabeth II HSC, Halifax Infirmary Site

Halifax, Nova Scotia, B3H 3A7, Canada

Location

McGill University Health Centre

Montreal, Quebec, H4A 3J1, Canada

Location

Limitations and Caveats

Early termination in McGill branch due to limited ability to recruit.

Results Point of Contact

Title
Katy Schurman
Organization
DMF Medical Inc.

Study Officials

  • Orlando Hung, MD

    Nova Scotia Health Authority

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
LTE60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 12, 2016

First Posted

January 9, 2017

Study Start

March 20, 2017

Primary Completion

May 10, 2022

Study Completion

July 24, 2024

Last Updated

February 23, 2026

Results First Posted

February 23, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations