Effect of Combined Fatty Acid Supplementation and Eccentric Exercise Training on Exercise Performance

NCT03259412 | Completed

• 1 other identifier: LoughboroughU
• Study Type: interventional
• Target: 18
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to determine whether fish oil (specifically omega-3 long chain polyunsaturated fatty acids \[EPA-DHA\]) supplementation can enhance eccentric resistance exercise performance when combined with a resistance exercise training study. The investigators aim to establish the potential mechanisms that might mediate performance changes at a cellular level.

Conditions

Exercise-induced Inflammation

Outcome Measures

Primary Outcomes (2)

• Strength

  Quadriceps and Hamstring strength using an isokinetic dynamometer

  Change from baseline strength at 11 weeks

• Leg power

  Dynamic leg power assessed through jump height on force platform

  Change from baseline strength at 11 weeks

Study Arms (2)

Fish Oil

EXPERIMENTAL

Fish oil 5.1g/ day - Premium Omega-3, Norwegian Pure-3, Oslo, Norway

Dietary Supplement: Fish Oil

Placebo

PLACEBO COMPARATOR

Olive Oil 6g/ day - Premium Omega-3, Norwegian Pure-3, Oslo, Norway

Dietary Supplement: Placebo

Interventions

Fish Oil DIETARY_SUPPLEMENT

Fish Oil Capsule

Also known as: n-3 PUFA, Omega-3

Fish Oil

Placebo DIETARY_SUPPLEMENT

Olive Oil capsule manufactured to mimic fish oil capsule

Also known as: Olive Oil

Placebo

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Males
• Healthy

You may not qualify if:

• Resistance exercise training within the past 6 months
• Vitamin or fish oil supplementation over the past 6 months
• Habitual use of anti-inflammatory drugs
• History of heart disease
• History of coagulation/bleeding disorder
• History of metabolic disease
• Serious allergy
• Known to have blood-borne virus
• Females (Due to differences in cell membrane incorporation of Omega-3 between the sexes and the testing schedule being unable to fit in with menstrual cycle, altering the blood markers that are being measured)
• Currently no symptoms of general illness

Sponsors & Collaborators

• Loughborough University: lead

Study Sites (1)

Loughborough University

Leicester, LE11 3TU, United Kingdom

Location

MeSH Terms

Interventions

Fish Oils; Fatty Acids, Omega-3; Docosahexaenoic Acids; Olive Oil

Intervention Hierarchy (Ancestors)

Oils; Lipids; Dietary Fats, Unsaturated; Dietary Fats; Fats; Fatty Acids, Unsaturated; Fatty Acids; Fats, Unsaturated; Plant Oils; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Lynsey S Wilson, MSc

  Loughborough University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Technical Tutor in Exercise Physiology/ PhD Student

Study Record Dates

• First Submitted: August 4, 2017
• First Posted: August 23, 2017
• Study Start: January 1, 2016
• Primary Completion: December 20, 2017
• Study Completion: December 20, 2017
• Last Updated: March 27, 2018

Record last verified: 2018-03

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)