Comparison of Perilipin, Leptin, Adipolipin, Adiponectin, Resistin, Visfatin, Estrone Levels Pre-post Omentectomy
1 other identifier
interventional
25
1 country
1
Brief Summary
Omentum is adipose tissue lying under inner anterior wall Omentectomy is routine procedure in treatment of gynecological malignancy especially ovarian cancer and some advanced stage endometrial cancer. Perilipin, Leptin, Adipolipin, Adiponectin, Resistin, Visfatin, Estrone secrete from adipose tissue. These regulate matabolic process. We aimed comparison of Perilipin, Leptin, Adipolipin, Adiponectin, Resistin, Visfatin, Estrone levels derivated from adipose tissue pre-postoperatively in patient diagnosed with gynecological malignancy performed omentectomy or not
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2017
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2017
CompletedFirst Submitted
Initial submission to the registry
August 15, 2017
CompletedFirst Posted
Study publicly available on registry
August 23, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2018
CompletedAugust 6, 2019
August 1, 2019
1.9 years
August 15, 2017
August 5, 2019
Conditions
Outcome Measures
Primary Outcomes (2)
with omentectomy group
Pre-postoperative levels of Perilipin, Leptin, Adipolipin, Adiponectin, Resistin, Visfatin, Estrone
1 year
No omentectomy group
Pre-postoperative levels of Perilipin, Leptin, Adipolipin, Adiponectin, Resistin, Visfatin, Estrone
1 year
Study Arms (3)
omentectomy
ACTIVE COMPARATORPreoperative
Omentectomy
OTHERPostoperative
No omentectomy
OTHERPreoperative post operative
Interventions
Blood sample
Eligibility Criteria
You may qualify if:
- gynecologic malignancy, staging surgery with or without omentectomy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Bakirkoy Dr Sadi Konuk Training and Research Hospital
Istanbul, 34000, Turkey (Türkiye)
Related Publications (1)
Comba C, Ozdemir IA, Demirayak G, Erdogan SV, Demir O, Ozlem Yildiz G, Bulut H, Karakas S, Gulseren V, Afsar S, Gungorduk K. The effect of omentectomy on the blood levels of adipokines in obese patients with endometrial cancer. Obes Res Clin Pract. 2022 May-Jun;16(3):242-248. doi: 10.1016/j.orcp.2022.06.002. Epub 2022 Jun 11.
PMID: 35701296DERIVED
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Head of Department of Gynecologic Oncology Bakirkoy Dr Sadi Konuk Training and Research Hospital
Study Record Dates
First Submitted
August 15, 2017
First Posted
August 23, 2017
Study Start
February 1, 2017
Primary Completion
December 31, 2018
Study Completion
December 31, 2018
Last Updated
August 6, 2019
Record last verified: 2019-08
Data Sharing
- IPD Sharing
- Will not share
IPD will not share other researchers due to participant individual preference but when the research result publish researchers may obtain