NCT03257657

Brief Summary

Low-income and minority women are at increased risk for postpartum weight retention (i.e. retaining weight after pregnancy) and consequent persistent obesity. Women who are obese pre-pregnancy are 3-5 times more likely to gain weight, rather than lose weight, in the postpartum period than non-obese women. Aims for this pilot study are listed below: Aim 1: To evaluate the feasibility and acceptability of a multi-component novel weight loss intervention delivered in a WIC setting to a population of low-income, predominantly racial/ethnic minority, obese, postpartum women. Aim 2: To evaluate differences in weight change, diet, physical activity, self-efficacy, readiness to change, motivations to eat between intervention and control participants to determine preliminary intervention efficacy over a 12-week period.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
42

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 31, 2017

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

August 1, 2017

Completed
21 days until next milestone

First Posted

Study publicly available on registry

August 22, 2017

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 22, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 22, 2018

Completed
2.1 years until next milestone

Results Posted

Study results publicly available

March 20, 2020

Completed
Last Updated

March 20, 2020

Status Verified

March 1, 2020

Enrollment Period

7 months

First QC Date

August 1, 2017

Results QC Date

May 31, 2019

Last Update Submit

March 6, 2020

Conditions

Outcome Measures

Primary Outcomes (5)

  • Feasibility of Recruitment

    The investigators plan to determine the feasibility of recruitment for a weight loss intervention by evaluating the rate of recruitment. Below describes number recruited/enrolled over 14 weeks of recruitment

    Once the final participant is recruited

  • Attrition Rate of Subjects Enrolled in the Study

    The investigators will measure the number of dropouts/withdrawn once final participant has completed the 12 week visit.

    Once the final participant completes the 12 week visit

  • Visit Attendance

    The investigators will measure lifestyle group participant attendance from enrollment through the 12-week visit. The number of participants who attended their visits is reported

    Baseline through Week 12, reported at Week 12

  • Acceptability of a Weight Loss Intervention

    To determine acceptability, investigators will use qualitative interviews to ask open-ended questions on this topic including asking participants in the intervention whether they would participate again. The number of participants interviewed who indicated that they would participate again is reported.

    12 weeks

  • Evaluation of the Use of Phone Coaching

    Investigators will count the total number of times any participant used phone coaching.

    12 weeks

Secondary Outcomes (8)

  • Change in Weight Between Visits

    Intervention group: Baseline, 12 weeks; Control group: Baseline and 12 weeks

  • Changes in Diet: Intakes Measured in Grams

    Baseline and 12 weeks

  • Changes in Physical Activity

    Baseline and 12 weeks

  • Changes in Diet and Physical Activity Self-efficacy

    Baseline and 12 weeks

  • Changes in Motivations to Eat

    Baseline and 12 weeks

  • +3 more secondary outcomes

Study Arms (2)

Observational Group

EXPERIMENTAL

Intervention: Participants will receive usual WIC care plus they will be given a packet of written WIC materials on lifestyle recommendations at the baseline visit, and offered an appointment with a WIC Registered Dietitian (RD) at the 12 week visit.

Behavioral: Observation Group participants

Lifestyle Group

EXPERIMENTAL

Intervention: Visits with WIC staff at Baseline, 4 weeks, 8 weeks: Meet with WIC staff who will use motivational interviewing during visits. Participants will complete an iPad app that asks lifestyle questions. Responses are provided to WIC staff in an easy to read format to guide lifestyle counseling and informational handouts are provided to participants. In-between visits: Participants receive text messages with informational and motivational content. They are invited to a Facebook private group providing informational and motivational content and encouraging cross-support amongst participants. They are asked to self-monitor activity and weekly weights and will be offered weekly phone coaching appointments with WIC staff.

Behavioral: Lifestyle group participants

Interventions

Women in the observation group will receive usual WIC care, plus the opportunity to meet with a WIC Registered Dietitian (RD) at the 12 week visit. Written WIC materials on lifestyle recommendations will also be given to all observation group participants at the baseline visit. The Investigators will connect with the participant prior to the 12 week visit to make an appointment to meet with the WIC RD at that time.

Observational Group

Women in this group will receive typical WIC care plus the below described activities. The intervention will last 12 weeks.

Lifestyle Group

Eligibility Criteria

Age18 Years - 50 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Adult woman (≥18 and \<50 years old).
  • Enrolled in WIC or with an infant enrolled in WIC.
  • months postpartum.
  • A pre-pregnancy BMI of 25 - 40 kg/m2 (based on self-reported height and weight prior to pregnancy).
  • Postpartum body mass index between 25 and 50 kg/m2.
  • English- and/or Spanish-speaking.
  • Owns a mobile phone with texting functionality in order to receive texts during the trial.

You may not qualify if:

  • Health conditions impacting weight or ability to participate in a weight loss trial.
  • Pregnancy or planned pregnancy in next 5 months.
  • Any health problems or undergoing any treatments that might interfere with what participant eats or her ability to exercise.
  • Medical provider recommendation to avoid exercise.
  • Plans to be in a different geographic area within the next 5 months.
  • Plans to stop coming to Aurora WIC in the next 5 months.
  • Unable to give informed consent.
  • Not able to read and understand English or Spanish at an 8th grade level.
  • Not willing to create a Facebook account if they do not already have one.
  • Asked to follow-up in \< 3 months at most recent WIC visit.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Aurora WIC Office

Aurora, Colorado, 80011, United States

Location

University of Colorado

Aurora, Colorado, 80045, United States

Location

MeSH Terms

Conditions

Weight LossObesity

Condition Hierarchy (Ancestors)

Body Weight ChangesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsOverweightOvernutritionNutrition DisordersNutritional and Metabolic Diseases

Results Point of Contact

Title
Darcy Thompson, Associate Professor
Organization
University of Colorado

Study Officials

  • Darcy A Thompson, MD, MPH

    University of Colorado, Denver

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: This is a pilot, randomized controlled trial. The investigators will pilot a multi-component intervention delivered in a WIC (Women, Infants, children) setting.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 1, 2017

First Posted

August 22, 2017

Study Start

July 31, 2017

Primary Completion

February 22, 2018

Study Completion

February 22, 2018

Last Updated

March 20, 2020

Results First Posted

March 20, 2020

Record last verified: 2020-03

Data Sharing

IPD Sharing
Will not share

Locations