Does Obesity Influence Women Cardiorespiratory Fitness and Daily Physical Activities? (ACTIVOB)

NCT03233061 | Completed

• 1 other identifier: 2017001
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

Many obese individuals experience difficulties in executing household activities. In this study, we investigate the cardiorespiratory fitness (CRF) of obese vs. non-obese women, and the impact of obesity on cardiorespiratory functioning during daily household activities.

Conditions

Obesity

Keywords

Obesity; cardiorespiratory fitness; oxygen uptake; household activities; physical activity; sedentary; intensity; obese women

Outcome Measures

Primary Outcomes (1)

• Comparison of relative peak oxygen consumption between obese and non-obese women , mesured with indirect calorimetry

  ⩒O2 peak comparison between OB vs NO women. For each household activity, the intensity expressed by the ratio ⩒O2 activity/resting ⩒O2 or the ratio ⩒O2 activity /⩒O2 peak will be compared between NO and OB

  2 months

Study Arms (2)

NO

ACTIVE COMPARATOR

NON OBESE WOMEN GROUP ( same age and same physical activities ) cardiorespiratory exercise testing with evaluation of peak oxygen uptake, heart rate and maximal cycling power output. Cardiorespiratory functioning is assessed during household activities such as ironing,cleaning floor,walking and climbing stairs.

Diagnostic Test: cardiorespiratory fitness and daily physical activities evaluations

OB

EXPERIMENTAL

OBESE GROUP cardiorespiratory exercise testing with evaluation of peak oxygen uptake,heart rate and maximal cycling power output.Cardiorespiratory functioning is assessed during household activities such as ironing, cleaning floor, walking and climbing stairs

Diagnostic Test: cardiorespiratory fitness and daily physical activities evaluations

Interventions

cardiorespiratory fitness and daily physical activities evaluations DIAGNOSTIC_TEST

The cardiopulmonary exercise testing is performed on a cycle ergometer connected to cardiovascular and respiratory software. Subjects have a facemask, which collected respiratory and metabolic variables.An incremental exercise test is performed up to exhaustion. ⩒O2 is recorded and heart rate is averaged by an electrocardiogram system. Cardiopulmonary exercise testing during household activities Subjects have to perform 3 everyday life household activities: ironing,cleaning floor,walking and climbing stairs.A wearable ambulatory indirect metabolic system is used with Holter mode to record cardiorespiratory measures.Subjects have to breathe through the K4b2 facemask and turbine.

NO; OB

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Body Mass Index (BMI = weight in kilograms/(height in meters) x (height in meters)) as: healthy obese (OB group (OB); BMI between 30 to 39.9 kg.m-2; n = 20), and healthy non obese (NO group (NO); BMI between 18.5 to 24.9 kg.m-2; n = 28).

You may not qualify if:

• comorbidities (other than obesity) :
• history of systemic hypertension or antihypertensive medication, diabetes mellitus, cardiovascular or respiratory disease, systemic disease, smoking;
• any drugs;
• BMI \>40 kg.m-2;
• having a regular physical activity.

Sponsors & Collaborators

• Laboratory of Movement, Condorcet, Tournai, Belgium: lead

Study Sites (1)

LAboratoire de l'effort et du mouvement

Tournai, HAinaut, 7500, Belgium

Location

MeSH Terms

Conditions

Obesity; Motor Activity; Sedentary Behavior

Interventions

Cardiorespiratory Fitness

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Physical Fitness; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Health; Population Characteristics

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Laboratory Head

Model Details: Women OBESE group VS Women NON-OBESE group

Study Record Dates

• First Submitted: July 26, 2017
• First Posted: July 28, 2017
• Study Start: March 1, 2017
• Primary Completion: March 28, 2017
• Study Completion: July 20, 2017
• Last Updated: August 1, 2017

Record last verified: 2017-07

Data Sharing

• IPD Sharing: Will not share

Locations

BE (1)