Life Plans Intervention Study

NCT03215901 | Completed Results

• 2 other identifiers: H-365915K01MH105320
• Study Type: interventional
• Target: 430
• Locations: 1 country
• Sites: 1

Brief Summary

The mass provision of HIV treatment in rural KwaZulu-Natal, South Africa has raised adult life expectancy by 18 years since 2003. We will conduct a population-based survey to assess young adults' beliefs about HIV, HIV treatment, and expectations for the future in the era of mass HIV treatment. Thh investigators will conduct a randomized evaluation to assess whether a short video providing young adults with information on longevity gains from HIV treatment affects young adults survival expectations, hope for the future, and health and educational behaviours, including uptake of HIV testing, the study's primary outcome.

Conditions

HIV/AIDS; Chronic HIV Infection; Health Knowledge, Attitudes, Practice

Keywords

Population-based survey; HIV treatment; HIV testing; Survival expectations; Condom use; Life plans; South African young adults

Outcome Measures

Primary Outcomes (1)

• Number of Participants Who Participated in HIV Testing

  Participants were provided a voucher at baseline for free HIV testing at a private pharmacy in the area. This voucher could be used at any time within four weeks after baseline. Participants were also visited by an AHRI demographic and health surveillance team approximately six weeks after baseline during which all household members were offered a home-based rapid HIV test. This outcome takes the value of 1 if the participant used the HIV testing voucher OR participated in HIV testing during the household surveillance visit, and zero if the participant did not use the HIV testing voucher AND did not participate in HIV testing during the household surveillance visit.

  6 weeks

Secondary Outcomes (7)

• Use of HIV Testing Voucher

  4 weeks

• Participation in HIV Testing or Care Services

  3 months

• Attendance at Job Search Skills Workshop

  2 weeks

• Condoms Purchased

  Immediate post-test

• Money Allocated to Savings Tin

  Immediate post-test

Study Arms (3)

A Beautiful Future Video

EXPERIMENTAL

Participants randomized to intervention will view intervention video.

Behavioral: A Beautiful Future Video

Active Control Video

SHAM COMPARATOR

Participants randomized to control will watch a video of similar length as the intervention video on a different topic.

Behavioral: Active Control Video

Pure Control

NO INTERVENTION

Participants view no video.

Interventions

A Beautiful Future Video BEHAVIORAL

Video delivering information on the longevity gains due to HIV treatment in the area.

A Beautiful Future Video

Active Control Video BEHAVIORAL

Video on another topic.

Active Control Video

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• resides in Africa Health Research Institute demographic surveillance area, specifically bounded structures to be visited during the last trimester of the surveillance in the "Southern PIPSA" area.
• member of a household in the AHRI demographic surveillance
• to 25 years of age

You may not qualify if:

• \<18, \>25 years
• not a member of a household under surveillance
• not resident in the surveillance area

Sponsors & Collaborators

• Boston University: lead
• National Institute of Mental Health (NIMH): collaborator
• Africa Health Research Institute: collaborator

Study Sites (1)

Africa Health Research Institute

Somkhele, KwaZulu-Natal, South Africa

Location

MeSH Terms

Conditions

Acquired Immunodeficiency Syndrome; Behavior

Condition Hierarchy (Ancestors)

HIV Infections; Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Slow Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases

Results Point of Contact

• Title: Jacob Bor, Assistant Professor
• Organization: Boston University

jbor@bu.edu

617-358-2176

Study Officials

• Jacob Bor, SD

  Assistant Professor

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 6, 2017
• First Posted: July 12, 2017
• Study Start: September 6, 2017
• Primary Completion: December 14, 2017
• Study Completion: December 14, 2017
• Last Updated: June 17, 2020
• Results First Posted: June 17, 2020

Record last verified: 2018-09

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: Data will be archived and publicly available within two years after data collection, and will be available indefinitely.
• Access Criteria: Data use request to Africa Health Research Institute

Locations

ZA (1)