Effect of Local Anaesthetic Dilution on the Characteristics of Ultrasound Guided Axillary Brachial Plexus Block

NCT03207035 | Completed Results

• 1 other identifier: ECM 4 (mm)
• Study Type: interventional
• Target: 20
• Locations: 0 countries
• Sites: N/A

Brief Summary

We propose to compare the effects of local anaesthetic dilution on the characteristics of the ultrasound guided axillary brachial plexus block. Administration of 40ml lidocaine 1% with epinephrine will shorten the onset time of ultrasound guided axillary brachial plexus block when compared to 20 mL lidocaine 2% with epinephrine for elective upper limb surgical procedures.

Conditions

Brachial Plexus Blockade

Outcome Measures

Primary Outcomes (1)

• Onset of Axillary Block

  Time taken for onset of sensory and motor axillary brachial plexus block

  1 day

Secondary Outcomes (7)

• Duration of Sensory and Motor Block

  1 day

• Block Performance Data- Imaging Time

  1 Hour

• Needling Time

  1Hour

• Performance Time

  1 Hour

• No of Needle Pass

  1 Hour

Study Arms (2)

20 ml of lidocaine 2% with epinephrine

ACTIVE COMPARATOR

Patients will receive axillary brachial plexus block with 20 ml of lidocaine 2% with epinephrine.

Procedure: Axillary brachial plexus block

40 ml 0f lidocaine 1% with epinephrine

EXPERIMENTAL

Patients will receive axillary brachial plexus block with 20 ml of lidocaine 1% with epinephrine diluted with 20 ml of nacl 0.9% ( total 40 ml)

Procedure: Axillary brachial plexus block

Interventions

Axillary brachial plexus block PROCEDURE

Ultrasound guided axillary brachial plexus block with local anaesthetic lidocaine with epinephrine

20 ml of lidocaine 2% with epinephrine; 40 ml 0f lidocaine 1% with epinephrine

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ASA 1-3
• Patients aged \>18 years undergoing elective upper limb (forearm or hand) surgical procedures.

You may not qualify if:

• Contraindications to regional anaesthesia
• Hypersensitivity to amide local anaesthetics.
• Chronic pain
• Language barrier
• Neuromuscular disorders or peripheral neuropathy
• Body mass index \> 35
• History of hepatic and renal insufficiency
• Pregnancy
• Cognitive or psychiatric disorder
• Cardiac conduction abnormality.

Sponsors & Collaborators

• Cork University Hospital: lead

Results Point of Contact

• Title: Dr Anil Ranganath
• Organization: Cork University Hospital

drmrak.2@gmail.com

Study Officials

• Anil Ranganath, FCAI

  Cork University Hospital

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr (Fellow in Regional Anaesthesia)

Study Record Dates

• First Submitted: May 7, 2017
• First Posted: July 2, 2017
• Study Start: October 15, 2014
• Primary Completion: March 14, 2016
• Study Completion: March 14, 2016
• Last Updated: October 18, 2021
• Results First Posted: October 18, 2021

Record last verified: 2021-10

Data Sharing

• IPD Sharing: Will not share