Estimation Method of 24-hour Urinary Sodium Excretion by Using Spot Urine for Chinese Population
The Exploratory and Validation Study of Estimation Method of 24-hour Urinary Sodium Excretion by Using Spot Urine for Chinese Children and Adults
1 other identifier
observational
330
1 country
1
Brief Summary
The accurate evaluation of daily salt or sodium intake is difficult to implement in clinical practice and large epidemiological studies. 24-h urinary sodium excretion (USE) is considered the gold standard, but is expensive and has a high participant burden. To further explore the association between 24-h USE and spot urines in Chinese population, it was proposed that using collected multiple spot urine samples could be estimated for 24-h USE in Chinese children and adults.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2017
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2017
CompletedFirst Submitted
Initial submission to the registry
June 28, 2017
CompletedFirst Posted
Study publicly available on registry
July 2, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 31, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2021
CompletedMarch 2, 2022
February 1, 2022
4.6 years
June 28, 2017
February 28, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
urinary sodium excretion concentration
the concentration measured by laboratory examination for the 24 hour urine sample and spot urine samples
day 1
Study Arms (2)
Children's group
no intervention. participants, whose age was 5 to 18 years, were enrolled in Children's group.
Adults group
no intervention. participants, whose age was over 18 years, were enrolled in Adults group.
Interventions
Eligibility Criteria
The children participants will be childrens from children's health care center and some inhospital patients from ophthalmology and orthopaedics ward in Beijing Children's Hospital. The adult participants will be residents from community.
You may qualify if:
- Aged 5-60 years
- Provide written informed consent
- Without any renal diseases or conditions which could affect renal function
You may not qualify if:
- Pregnant
- Taking diuretic medicine or pharmaceutical using patients, e.g. some hypertension or heart diseases patients
- Cancer patients or some other severe patient
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Beijing Children's Hospitallead
- Capital Medical Universitycollaborator
Study Sites (1)
Beijing Children's Hospital
Beijing, China
Biospecimen
the 24-h urine sample and the spot urine samples will be required collected and be retained.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Yaguang Peng, PhD
Beijing Children's Hospital
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- research assistant
Study Record Dates
First Submitted
June 28, 2017
First Posted
July 2, 2017
Study Start
February 1, 2017
Primary Completion
August 31, 2021
Study Completion
December 31, 2021
Last Updated
March 2, 2022
Record last verified: 2022-02
Data Sharing
- IPD Sharing
- Will not share