Artificial Intelligence to Assess the Association Between Facial Characteristics and Coronary Artery Diseases

NCT03731936 | Completed

• 1 other identifier: 20181104-2017-907
• Study Type: observational
• Target: 6,864
• Locations: 1 country
• Sites: 9

Brief Summary

The purposes of this study are 1) to explore the association between facial characteristics and the increased risk of coronary artery diseases; 2) to evaluate the diagnostic efficacy of appearance factors for coronary artery diseases.

Conditions

Coronary Artery Disease

Keywords

artificial intelligence; facial characteristics

Outcome Measures

Primary Outcomes (1)

• Sensitivity of diagnostic model

  The sensitivity of coronary artery diagnostic model assessed in model test group

  at the end of enrollment (6 months)

Secondary Outcomes (5)

• Specificity of diagnostic model

  at the end of enrollment (6 months)

• Specificity of diagnostic model

  at the end of enrollment (6 months)

• Positive predictive value (PPV)

  at the end of enrollment (6 months)

• Negative predictive value (NPV)

  at the end of enrollment (6 months)

• Diagnostic accuracy rate

  at the end of enrollment (6 months)

Study Arms (1)

Model establishment and test group

Patients undergoing coronary angiography or coronary computer tomography angiography will be enrolled. Patients data will be used to establish the facial based diagnostic model of coronary artery diseases, and to prospectively validate the diagnostic effectiveness of the model.

Other: No intervention

Interventions

No intervention OTHER

No intervention

Model establishment and test group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who undergo coronary angiography or coronary computer tomography angiography from both resident patients and outpatient.

You may qualify if:

• Undergoing coronary angiography or coronary computer tomography angiography
• Written informed consent

You may not qualify if:

• Prior percutaneous coronary intervention (PCI)
• Prior coronary artery bypass graft (CABG)
• Screening coronary artery disease before treating other heart diseases
• Without blood biochemistry outcome
• With artificially facial alteration (i.e. cosmetic surgery, facial trauma or make-up)
• Other situations which make patients fail to be photographed

Sponsors & Collaborators

• China National Center for Cardiovascular Diseases: lead

Study Sites (9)

Beijing Anzhen hospital

Beijing, Beijing Municipality, 100032, China

Location

Fuwai hospital

Beijing, Beijing Municipality, 100032, China

Location

Guanganmen Hospital, Chinese Academy of Traditional Chinese Medicine

Beijing, Beijing Municipality, 100032, China

Location

Wuhan union hospital

Wuhan, Hubei, 430000, China

Location

Xuzhou third people's hospital

Xuzhou, Jiangsu, 221000, China

Location

The first affiliated hospital of Dalian medical university

Dalian, Liangning, 116000, China

Location

Shanghai East hospital

Shanghai, Shanghai Municipality, 200000, China

Location

Shanghai Renji hospital

Shanghai, Shanghai Municipality, 200000, China

Location

The fisrt affiliated hospital of Wenzhou medical university

Wenzhou, Zhejiang, 325000, China

Location

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 4, 2018
• First Posted: November 6, 2018
• Study Start: July 10, 2017
• Primary Completion: August 2, 2019
• Study Completion: August 2, 2019
• Last Updated: August 20, 2019

Record last verified: 2019-08

Data Sharing

• IPD Sharing: Will not share

Locations

CN (9)